In a nutshell This study aimed to investigate the association of uric acid levels before a stem cell transplant and patient outcomes. This study concluded that high uric acid levels before the transplant led to increased mortality. Some background Uric acid is a product of metabolic breakdown and is a normal component of urine. It...
Read MoreType of leukemia-Acute Myeloid Leukemia (AML) Posts on Medivizor
The effect of uric acid levels on the outcomes of patients having an allogeneic stem cell transplant
In a nutshell This study aimed to investigate the association of uric acid levels before a stem cell transplant and patient outcomes. This study concluded that high uric acid levels before the transplant led to increased mortality. Some background Uric acid is a product of metabolic breakdown and is a normal component of urine. It can also be a...
Read MoreComparing conditioning regimens for patients with acute myeloid leukemia who will receive a transplant
In a nutshell This study aimed to investigate the long-term survival outcomes for patients with acute myeloid leukemia receiving conditioning regimen involving fractionated total body irradiation combined with cyclophosphamide or etoposide before transplant. This study concluded that this...
Read MoreStem cell transplant in patients in second complete remission with core binding factor acute myeloid leukemia.
In a nutshell This study aimed to investigate the outcomes of allogeneic transplantation in patients with core-binding factor acute myeloid leukemia in second complete remission. This study concluded that transplant was effective in a large proportion of these patients. Some background Core binding factor acute myeloid...
Read MoreSurviving cancer – is there a greater risk of cardiovascular disease long-term?
In a nutshell This study investigated if there is a higher risk of cardiovascular disease (CVD) in cancer survivors. They found that cancer survivors have a higher risk of CVD. Some background Improved cancer detection and treatment has increased the rates of survival. The number of cancer survivors living for more than 10 years is growing. Some...
Read MoreEvaluating the TLI-ATG conditioning regimen before allogeneic stem cell transplantation in patients with lymphoma or leukemia
In a nutshell This study evaluated the safety and effectiveness of total lymphoid irradiation and anti-thymocyte globulin (TLI-ATG) conditioning before stem cell transplantation (SCT) in patients with lymphoma or leukemia. This study concluded that this regimen was well-tolerated and effective, especially for patients who had multiple lines of prior...
Read MoreFertility options for female patients with lymphoma or leukemia
In a nutshell This article reviewed different options to preserve or restore fertility in female patients with lymphoma or leukemia. Some background Impaired reproductive function is one possible side effect of aggressive chemotherapy and radiotherapy for cancer. In severe cases, intensive anti-cancer treatment can lead to fertility loss. 7 to 9% of...
Read MoreEvaluating the safety and effectiveness of the Shingrix vaccine for patients with leukemia or lymphoma
In a nutshell This study evaluated the safety and effectiveness of the herpes zoster vaccine (Shingrix) in patients with blood cancer who are receiving anti-cancer therapy. This study concluded that the Shingrix vaccine was effective in these patients, with manageable side effects. Some background Shingles is caused by a virus called herpes zoster....
Read MoreLong-term risk of infections after treatment of childhood leukemia
In a nutshell This study aimed to compare the risk of infections after treatment completion for pediatric leukemia survivors and the general population. This study concluded that there was a significant association between history of leukemia therapy and increased risk of infections. Some background Infections are a common...
Read MoreChemotherapy alternatives for children with acute myeloid leukemia
In a nutshell This study aimed to identify an effective and safe chemotherapy for children with acute myeloid leukemia (AML). This study concluded that clofarabine during remission induction may reduce the need for other treatments which cause side effects in these patients. Some background Clofarabine...
Read MoreLooking for patients with relapsed or unresponsive acute myeloid leukemia to test a new targeted therapy drug
In a nutshell This trial is examining the effectiveness of crenolanib after salvage chemotherapy for relapsed or unresponsive acute myeloid leukemia (AML) with FLT3 activating mutations. The main outcome would be survival without complications from leukemia 3 years after the treatment has finished. The details AML is a type of blood...
Read MoreEvaluating strategies to preserve fertility in cancer patients
In a nutshell This study investigated female fertility preservation (FFP) in cancer patients. They found that FFP should be discussed with all women of reproductive age undergoing cancer treatment. Some background Cancer can have many negative effects on patient health. Infertility is a particular concern for younger female patients. Pregnancy rates...
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