In a nutshell This study evaluated the rates of local, regional, and distant recurrence between patients who received immediate or delayed autologous deep inferior epigastric perforators (DIEP) flap breast reconstruction (BR). The data showed that there is an increased risk for breast cancer (BC) recurrence in women who received a delayed BR...
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In a nutshell This study evaluated the effectiveness of adding targeted therapy to chemotherapy before surgery for the treatment of patients with inflammatory breast cancer (IBC). The data showed that adding targeted therapy is more effective than chemotherapy alone for these patients. Some background IBC is a rare and aggressive form of...
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In a nutshell This study evaluated the impact of different times after chemotherapy until breast cancer surgery on complications after surgery and survival outcomes. The data showed the optimal time to surgery (TTS) was between 21 and 28 days after chemotherapy in these patients. Some background Breast cancer (BC) is one of...
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In a nutshell This study evaluated the role of circulating tumor cells (CTCs) in deciding adjuvant therapy (AT; treatment after surgery) in patients with breast cancer (BC). This study showed that personalized AT based on CTCs improved patient survival. Some background BC that has not spread to other areas of the body is called non-metastatic...
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In a nutshell This study was carried out to assess the use of radiotherapy (RT) after mastectomy (surgical removal of the breast) for triple-negative breast cancer (TNBC) that has spread to the lymph nodes. The authors found that RT after surgery was associated with improved survival in patients with larger tumors. Some background Triple-negative...
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In a nutshell This article aimed to examine the effectiveness of an immediate breast reconstruction (IBR) approach using DIEP-flap repair and compared it to the standard treatment of a delayed breast reconstruction (DBR) in women with breast cancer (BC) undergoing mastectomy (breast removal surgery). The authors concluded that IBR should be...
Read MoreIn a nutshell This study evaluated whether treating breast cancer that has not been completely removed with more surgery was more effective than non-surgical options such as chemotherapy. This study found that there was no difference in outcomes between treating with further surgery versus treating with a non-surgical option. Some...
Read MoreIn a nutshell The trial aims to investigate a new way of delivering radiation therapy in women with early-stage breast cancer. This will involve low doses of radiation therapy being aimed at the part of the breast where the tumor is or was. The main outcomes that will be measured are side effects and recurrence rate. This trial is recruiting in Missouri,...
Read MoreIn a nutshell This trial is examining the effectiveness of chemotherapy and atezolizumab (Tecentriq), given before surgery, for triple negative breast cancer. The main outcomes to be measured will be response in the breast tissue and lymph nodes and survival. The details Triple negative breast cancer is not dependent on the HER2 receptors or...
Read MoreIn a nutshell This study looked at the impact of removing lymph nodes (immune glands) from the armpit (axillary nodes) in the treatment of patients with breast cancer. The study found that removing the axillary lymph nodes did not signifcantly improve survival in patients with early stage breast cancer. Some background Breast cancer has the...
Read MoreIn a nutshell This trial is examining the effectiveness of pulsed electromagnetic field (PEMF) or an anesthetic bupivacaine in lowering the incidence of chronic pain after surgery. The main outcome to be measured will be the incidence of chronic pain after each treatment. This study is being conducted in New York City. The...
Read MoreIn a nutshell This study investigated the accuracy and reliability of sentinel lymph node biopsy (SNLB) before neoadjuvant systemic therapy (NAST) has begun in breast cancer patients. The study concluded that SLNB before NAST is highly reliable. The authors suggested that patients with a negative SLNB may be able to avoid lymph node removal and...
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