In a nutshell This study investigated the role of tumor budding (TB) in predicting the best treatment for stage 2 colon cancer. Researchers suggested that TB could improve the effect of chemotherapy after surgery in these patients. Some background Stage 2 colorectal cancer accounts for one-third of patients who undergo curative surgery. Prognostic...
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In a nutshell This study compared a 3-month with a 6-month chemotherapy treatment after colon cancer surgery. Researchers suggested that the duration of the treatment should be chosen according to the patient condition. Some background Colorectal cancer is one of the most common cancers worldwide. Stage 2 and 3 colon cancer are common and curable...
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In a nutshell This study investigated the best interval time between chemoradiation therapy and rectal cancer surgery for the best outcomes in patients with rectal cancer. Researchers suggested that waiting at least 8 weeks until the surgery increases the tumor response to the treatment. Some background The standard treatment for locally advanced...
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In a nutshell This study investigated the survival outcomes in patients with rectal cancer after surgery with and without radiation therapy (RT). Researchers suggested that RT after surgery is associated with improved outcomes. Some background Rectal cancer is one of the most common cancers worldwide. Between 15 to 20% of patients present metastatic...
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In a nutshell This study compared the effectiveness of two different types of radiation therapy to treat rectal cancer. Researchers suggested that high-dose endorectal brachytherapy (HDEB) is associated with improved tumor response. Some background The standard treatment for rectal cancer that has spread outside the rectum lining (T3 tumor) is...
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In a nutshell This study investigated the outcomes of patients with rectal cancer who received enhanced recovery pathway (ERP) in combination with surgery. Researchers suggested that ERP was associated with longer overall survival. Some background The standard treatment for rectal cancer is surgery, chemotherapy and radiation therapy. However, rectal...
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In a nutshell This study investigated the effectiveness and safety of consolidation chemotherapy after initial treatment in locally advanced rectal cancer. Researchers suggested that this treatment is safe and is associated with improved cancer outcomes. Some background Colorectal cancer is the fifth most common cancer. From all the colorectal...
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In a nutshell This study investigated if a change in white blood cell (WBC) levels before or during chemotherapy and radiation therapy are associated with rectal tumor response. Researchers suggested that a decreased level of WBC is associated with improved tumor response in patients with rectal cancer. Some background Chemotherapy and radiation...
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In a nutshell This study investigated whether adding mFOLFOX6 (modified; folinic acid, fluorouracil, and oxaliplatin) chemotherapy after standard chemotherapy and radiotherapy (CRT) and delaying surgery improves cancer response and survival in rectal cancer. Researchers suggest that this treatment increases disease-free survival (DFS;...
Read MoreIn a nutshell This study compared the outcomes of patients with rectal cancer treated with either laparoscopy (LPS; removal of the tumor by using a cable with a camera inserted near the tumor) or open surgery. Researchers found no differences in outcomes between LPS and open surgery for these patients. Some background Treatment for rectal...
Read MoreIn a nutshell This study investigated the outcomes of surgery to lung metastasis (LM; cancer spreads to the lungs) in patients with colorectal cancer. Researchers suggested that lung surgery increases the survival of these patients. Some background Colorectal cancer is one of the major diseases seen in the US. LM appear in 5-15% of patients and...
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In a nutshell This study investigated if delayed chemotherapy treatment after surgery is associated with improved colon cancer outcomes. Researchers suggested that patients should receive chemotherapy within 6-8 weeks after surgery. Some background The standard treatment for stage 3 colon cancer is surgery followed by chemotherapy. Some...
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