In a nutshell This study looked at the risk factors and protective factors surrounding non-alcoholic fatty liver disease in relation to tamoxifen (Novaldex) therapy for women with breast cancer. The authors found that a high BMI was a risk factor for tamoxifen related fatty liver disease, while exercise was a protective factor. Some background...
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In a nutshell This study aimed to compare different strategies of promoting bone health. This study found that educational strategies to improve bone health care are feasible and are associated with improved bone mineral density ordering in men receiving androgen deprivation therapy. Some background Bone health is important for men receiving...
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In a nutshell The aim of this study was to determine the effect of biomarkers to tailor therapy in advanced prostate cancer in patients receiving abiraterone (Zytiga) treatment. The authors concluded that alkaline phosphatase (ALP- protein elevated in the blood), lactate dehydrogenase (LDH – protein involved in tumor growth) and prostate...
Read MoreIn a nutshell The authors aimed to determine the effectiveness of apalutamide before or after treatment with abiraterone acetate (Zytiga) and prednisone (Deltasone) in men with advanced, hormone-resistant prostate cancer. The authors concluded that apalutamide was a safe treatment option and demonstrated effectiveness against advanced,...
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In a nutshell This study aimed to investigate the frequency and severity of the adverse events associated with non-hormonal drugs (NHD) used to treat hot flashes in breast cancer survivor patients. This study concluded that the use of high-dose NHD led to increased rates of adverse events when compared to patients not using NHD. Some...
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In a nutshell The authors aimed to determine the impact of prostate specific antigen (PSA) surge in hormone-resistant prostate cancer patients following abiraterone acetate (Zytiga) treatment. The authors concluded that PSA surge occurred in both chemotherapy-treated and chemotherapy-naïve patients treated with abiraterone acetate with no...
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In a nutshell The aim of this study was to determine whether the neutrophil to lymphocyte ratio (NLR) can be used to determine outcome in CRPC patients treated with enzalutamide (Xtandi). It was concluded that NLR could be used to predict the outcome for CRPC patients treated with enzalutamide. Some background Treatment for metastatic...
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In a nutshell The aim of this study was to examine whether combining radiation therapy and antiandrogen therapy improved survival in patients with prostate cancer that is not cured by initial treatment. It was concluded that the combination of radiation therapy and antiandrogen therapy improved survival when compared to radiation therapy...
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In a nutshell This review examined the benefits of extending hormone therapy from 5 to 10 years in patients with hormone receptor positive breast cancer. The study concluded that treatment recommendations should take factors such as previous treatments and potential side effects into account. Some background Hormone-receptor (HR)-positive breast...
Read MoreIn a nutshell This study examined the effect of duration and different types of hormone therapy on the risk of developing type 2 diabetes in prostate cancer patients. Researchers concluded that the type and duration of hormone therapy significantly affected diabetes risk. Some background Hormone therapy is a common treatment used in prostate...
Read MoreIn a nutshell This study examined different treatment options for elderly men with localized prostate cancer. Researchers reported that radiation therapy with or without hormone therapy was associated with a significant survival benefit when compared to observation alone. Some background Localized prostate cancer refers to cancer that is confined...
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In a nutshell This study examined the effect of androgen deprivation therapy (ADT) on the risk of cardiovascular events (such as stroke or heart attack) in men treated with radiation therapy. Researchers concluded that ADT use during or after radiation therapy increases the risk of cardiovascular events. Some background Radiation therapy is a...
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