In a nutshell This study investigated the safety of hyperthermic intraperitoneal chemotherapy (HIPEC) and surgery in colon cancer patients with peritoneal metastasis (PM). Researchers reported that HIPEC and surgery was associated with an increased risk of complications. Some background When colon cancer spreads to the abdominal lining (known as...
Read MoreTreatment(s) now being considered-HIPEC Posts on Medivizor
Comparison of two treatments for colorectal cancer that has spread to the peritoneum
In a nutshell This study compared two treatments for peritoneal metastasis in colorectal cancer (cancer that has spread to the lining of the abdomen). Some background Peritoneal metastasis is a serious complication of colorectal cancer. It is not usually treatable with standard chemotherapy, which is injected into veins or given by...
Read MoreDefining patients with a high risk of developing peritoneal carcinomatosis after curative surgery
In a nutshell The objective of this study was to identify risk factors predictive for developing peritoneal carcinomatosis (PC) after curative surgery for colorectal cancer (CRC). The data show three situations that could result in a real risk of recurrent PC: synchronous PC, synchronous isolated ovarian metastases and a perforated primary tumor. There...
Read MoreThe right treatments are available if the correct trials are used to show that therapy is improving.
In a nutshell This editorial article published at The Journal of Clinical Oncology, expresses experts' opinion, criticizing the current practice and design of clinical trials involving patients with rectal cancer. Some background Despite improvements in treatment options, such as the addition of the platinum-based drug Oxaliplatin to...
Read MoreEvaluating the risks and benefits of treatment for abdominal cancer spread
In a nutshell The present study evaluated the long-term quality of life (QOL) for patients with peritoneal carcinomatosis (PC) who had cytoreductive surgery (CRS) and HIPEC (hyperthermic perioperative chemotherapy). Main findings: patients who survived the procedure regained their baseline (pre-operative) QOL within 6-12 months after...
Read MoreTreating tumors of the appendix to reduce the risk of spread to the abdominal cavity
In a nutshell The present study classified tumors of the appendix and reviewed treatments that aim to prevent cancer spread to the abdominal cavity. Some background Pseudomyxoma peritonei (PMP) is a rare condition caused by the production of too much mucin (a protein that is secreted in mucus). PMP affects women more than men and symptoms...
Read MoreRisks versus benefit of the ‘HIPEC’ treatment for peritoneal metastases due to colorectal cancer
Colorectal cancer (CRC) often presents with peritoneal metastases, which have a poor outcome. This means that cancer cells have spread from the colon, appendix, or rectum to the peritoneum (a sheath that covers the abdominal organs). This article argues the pros and cons of a combined treatment for patients with peritoneal metastases from CRC. This...
Read MoreThe use of systemic chemotherapy for patients with poorly differentiated and signet cell adenocarcinoma of the appendix
In a nutshell The present study evaluated the effects of systemic chemotherapy and cytoreductive surgery (CRS) on survival in patients with aggressive types of cancer of the appendix (poorly differentiated and signet ring cell adenocarcinoma). The main findings were that systemic chemotherapy appears to be a viable treatment option for these types of...
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