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Treatment(s) already received-None Posts on Medivizor

Comparing obinutuzumab and rituximab in first-line chemotherapy regimens for follicular lymphoma

Posted by on Jul 2, 2018 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This study investigated the safety and effectiveness of obinutuzumab (Gazyva) versus rituximab (Rituxan) plus chemotherapy for previously untreated follicular lymphoma. This study concluded that obinutuzumab improved survival outcomes compared to rituximab. Some background Follicular lymphoma is the most common type of...

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What are the outcomes for advanced HL patients receiving intensified BEACOPP chemotherapy after ABVD chemotherapy?

Posted by on Feb 9, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study investigated the outcomes of advanced-stage classical Hodgkin’s lymphoma (HL) patients treated with ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine) chemotherapy followed by escalated (higher dose) BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone) chemotherapy...

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Looking for patients recently diagnosed with diffuse large B-cell lymphoma to test an immunotherapy after R-chemotherapy

Posted by on Sep 11, 2017 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This phase 2 clinical trial will test the safety and effectiveness of blinatumomab (Blincyto) after an R-chemotherapy in treating newly diagnosed patients with diffuse large B-cell lymphoma (DLBCL). The primary outcome will be measured by adverse (negative) side effects. The details Blinatumomab is an immunotherapy that uses the...

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Searching for newly diagnosed patients with B-lineage acute lymphoblastic leukemia to participate in a randomized immunotherapy trial

Posted by on Sep 11, 2017 in Leukemia | 0 comments

In a nutshell This phase 3 clinical trial will test the effectiveness of blinatumomab (Blincyto) with chemotherapy versus chemotherapy alone in treating patients with newly diagnosed B lineage acute lymphoblastic leukemia (ALL) that is BCR-ABL negative. The primary outcome will be measured by the overall survival. The details Blinatumomab is...

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Looking for patients with chronic lymphocytic leukemia with IGHV mutation to test a combination therapy

Posted by on Sep 11, 2017 in Leukemia | 0 comments

In a nutshell This phase 2 clinical trial will test the effectiveness of a combination treatment, consisting of ibrutinib (Imbruvica), fludarabine (Fludara), cyclophosphamide (Cytoxan), and obinutuzumab (Gazyva), in treating chronic lymphocytic leukemia (CLL). The primary outcome will be measured by the response to treatment. This trial is being...

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Quality of life after different types of radiation in early-stage breast cancer

Posted by on Feb 13, 2017 in Breast cancer | 0 comments

In a nutshell This study investigated the impact of whole breast radiation therapy (WBRT) and accelerated partial breast irradiation (APBI) on the severity of post-treatment side effects and quality of life. This study concluded that both forms of radiation therapy (RT) show similar survival benefits and similar quality of life in early-stage breast...

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The impact of cancer-related fatigue on Hodgkin lymphoma patients and survivors

Posted by on Feb 1, 2017 in Hodgkin's lymphoma | 0 comments

In a nutshell This study determined the impact of cancer-related fatigue on Hodgkin-Lymphoma patients and survivors. The authors concluded that fatigue particularly affected social integration.   Some background Hodgkin-Lymphoma (HL) patients and survivors can experience persistent cancer-related fatigue. Reports of fatigue occur 2.5 to 3...

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Who should receive radiotherapy after breast-conserving surgery for ductal carcinoma in situ?

Posted by on Feb 1, 2017 in Breast cancer | 0 comments

In a nutshell This study investigated the rate of loco-regional recurrence (LRR) when breast-conserving surgery (BSC) was not followed by radiotherapy. This study concluded that the rate of LRR was low in patients who did not undergo radiation after BCS, but that age and margin width were risk factors for LRR. Some background BCS is a surgery...

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Could immunotherapy be more beneficial than chemotherapy at treating some types of NSCLC?

Posted by on Dec 19, 2016 in Lung cancer | 0 comments

In a nutshell This trial determined whether pembrolizumab (Keytruda) is more effective at treating advanced NSCLC than chemotherapy in patients with high levels of a specific protein called PD-L1. The authors concluded that, for this subgroup of patients, pembrolizumab was more effective and safer than chemotherapy. Some background In some...

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