In a nutshell This study investigated the effectiveness and safety of consolidation chemotherapy after initial treatment in locally advanced rectal cancer. Researchers suggested that this treatment is safe and is associated with improved cancer outcomes. Some background Colorectal cancer is the fifth most common cancer. From all the colorectal...
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The use of brentuximab vedotin before transplant for patients with Hodgkin’s lymphoma
In a nutshell This study aimed to compare outcomes for patients with Hodgkin’s lymphoma who received brentuximab vedotin (Adcetris) compared to chemotherapy before a stem cell transplant. This study concluded that patients who received brentuximab vedotin had a better survival. Some background Allogeneic hematopoietic stem cell...
Read MoreDoes bone Hodgkin lymphoma affect survival in patients with Hodgkin lymphoma?
In a nutshell This study investigated if patients with Hodgkin lymphoma (HL) found in the bones have worse outcomes than patients with HL in the lymph nodes. It was found that having bone HL did not reduce survival of patients. Some background Many patients with HL are cured by treatment. After 5 years, almost 86% of patients survive. When...
Read MoreIs stem cell transplant more effective than other treatments for multiple myeloma?
In a nutshell This study compared the effects of stem cell transplant to other newer treatments for recently diagnosed multiple myeloma (MM). The main finding was patients who received stem cell transplant had better outcomes than those who did not. Some background Stem cell transplant involves the transfer of cells to a patient. This is an effective...
Read MoreEvaluating second-line rituximab-bendamustine treatment for patients with follicular lymphoma
In a nutshell This study evaluated the safety and effectiveness of the BR (bendamustine, rituximab) regimen as a second-line treatment for patients with follicular lymphoma (FL) who had disease progression (tumor growth or spread) after chemoimmunotherapy. The study concluded that this regimen was effective in these patients. Some background...
Read MoreBleomycin and the risk factors for lung problems in Hodgkin lymphoma.
In a nutshell This study investigated the risk factors of developing lung problems after bleomycin (Blenoxane) treatment for Hodgkin lymphoma (HL). It was found that older age may increase the risk of developing lung problems. Some background Bleomycin is an anti-cancer drug, used to treat many types of cancer. Bleomycin is commonly...
Read MoreEvaluating the use of PET scanning after first-line treatment for follicular lymphoma
In a nutshell This study evaluated the value of PET (positron emission tomography) scanning after first-line (primary) chemoimmunotherapy in patients with previously untreated follicular lymphoma (FL). This study concluded that PET scanning is a better imaging technique than CT (computed tomography) for assessing treatment response in these...
Read MoreEvaluating medical cannabis use in patients with Hodgkin’s lymphoma
In a nutshell This study investigated the effectiveness of medical cannabis in managing side effects associated with chemotherapy in patients with Hodgkin’s lymphoma (HL). This study concluded that medical cannabis may be effective in relieving therapy-related side effects in these patients. Some background Chemotherapy remains the standard...
Read MoreCognitive performance is affected by chemotherapy in patients with colorectal cancer
In a nutshell This study investigated the effects of chemotherapy after surgery on cognitive performance (CP; attention, memory and thinking processes) in patients with colorectal cancer. Researchers suggested that patients who received chemotherapy after surgery had a decreased CP. Some background Surgery followed by chemotherapy is the standard...
Read MoreCyroablation for the treatment of early stage prostate cancer
In a nutshell This study evaluated the long-term safety and effectiveness of cryoablation (a process that uses extreme cold to destroy tissue) for patients with early prostate cancer. This study found that cryoablation is safe and effective for early-stage prostate cancer. Some background Cryoablation is a treatment option for early-stage prostate...
Read MoreEvaluating Zevalin followed by stem cell transplantation for relapsed or refractory NHL
In a nutshell This study evaluated the safety and effectiveness of ibritumomab tiuxetan (Zevalin) followed by high-dose chemotherapy and autologous stem cell transplantation (ASCT) in patients with relapsed (cancer recurrence) or refractory (does not respond to treatment) non-Hodgkin’s lymphoma (NHL). This study concluded that ibritumomab tiuxetan...
Read MoreThe effects of Len/Dex combination therapy in relapsed multiple myeloma.
In a nutshell This study investigated the effects of lenalidomide/dexamethasone (Revlimid/Dexasone) combination treatment in relapsed multiple myeloma. The main finding was that the type of relapse may predict how a patient responds to lenalidomide/dexamethasone treatment. Some background Common treatments for multiple myeloma (MM) include...
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