In a nutshell The study evaluated the effectiveness of compression bandages applied with different pressures on the skin and subcutaneous tissue in patients with breast cancer-related lymphedema (BCRL). The study concluded that high-pressure compression bandage was more effective in reducing skin and subcutaneous tissue thickness and inflammation in...Read More
Treatment(s) already received-Chemotherapy Posts on Medivizor
Can oral azacitidine maintenance promote longer survival in older patients with acute myeloid leukemia in first remission following chemotherapy?
In a nutshell This study evaluated the effectiveness of oral azacitidine (Onureg; Oral-AZA) maintenance treatment in older patients with acute myeloid leukemia (AML) in remission. The data showed that Oral-AZA maintenance therapy can be considered in older patients with AML for which hematopoietic stem cell transplantation (HSCT) is not an...Read More
Comparing the effectiveness and safety of trastuzumab emtansine plus pertuzumab versus taxane plus trastuzumab plus pertuzumab in patients with high-risk HER2+ early breast cancer.
In a nutshell This study compared the effectiveness and safety of trastuzumab emtansine (T-DM1; Kadcyla) plus pertuzumab (Perjeta) versus taxanes plus trastuzumab (Herceptin) plus pertuzumab (THP) in patients with high-risk HER2-positive (+) early breast cancer (BC) after previous treatment with anthracycline-based chemotherapy. The data showed that...Read More
In a nutshell This study aimed to investigate depression and cognitive (thinking and reasoning) functions after taxane-based chemotherapy in patients with breast cancer. This study concluded taxane-based chemotherapy commonly leads to cognitive impairment in these patients, but some functions improve or remain stable after stopping...Read More
Survival of patients with rectal cancer followed-up by the watch and wait method after chemoradiotherapy
In a nutshell This study investigated the outcomes of patients with rectal cancer who were followed up with the watch and wait method after chemoradiotherapy (CRT). Researchers suggested that this strategy can effectively identify patients who can have a less frequent follow-up if they maintain response for the first 3 years...Read More
Allogenic versus autologous hematopoietic stem cell transplant for patients with acute promyelocytic leukemia
In a nutshell This study aimed to compare the outcomes of allogeneic (allo) and autologous (auto) hematopoietic stem cell transplant (HSCT) for patients with acute promyelocytic leukemia (APL) in second complete remission (CR2). This study concluded that autoHSCT resulted in better outcomes for these patients. Some background...Read More
Comparing the outcomes of utidelone plus capecitabine versus capecitabine alone in patients with previously treated resistant metastatic breast cancer
In a nutshell The study compared outcomes of utidelone plus capecitabine (Xeloda) versus capecitabine (C) alone in previously treated patients with anthracycline- and taxane-resistant metastatic breast cancer (MBC). The authors found that this combination improved survival compared to C alone in such patients. Some background...Read More
Evaluating pembrolizumab consolidation following chemotherapy and radiation for patients with stage III non-small cell lung cancer.
In a nutshell This trial was carried out to examine the effectiveness of pembrolizumab (Keytruda) consolidation therapy for patients with stage III unresectable non-small cell lung cancer (NSCLC) following a course of chemotherapy and radiation therapy. The authors found that pembrolizumab consolidation improved the outcomes of...Read More
In a nutshell The study compared the quality of life (QoL) of patients with metastatic castration-resistant prostate cancer (mCRPC) treated with cabazitaxel (Jevtana) compared to abiraterone (Zytiga) or enzalutamide (Xtandi). The authors found that cabazitaxel did not reduce QoL in such patients. Some background Patients with mCRPC...Read More
In a nutshell This study looked at using both chemotherapy and blinatumomab (Blincyto) prior to stem cell transplant (SCT) for patients with relapsed or unresponsive aggressive non-Hodgkin lymphoma (NHL). It found that blinatumomab is an effective second salvage for patients who did not fully respond to chemotherapy. Some background NHL is a...Read More
In a nutshell The study evaluated the contribution of chemotherapy on cancer-related cognitive impairment (CRCI) reported by women with early breast cancer. The authors found that chemotherapy added to hormonal therapy caused early and short-term CRCI in such patients, compared to hormonal therapy alone. Some background CRCI refers to problems in...Read More
In a nutshell This study examined if radiotherapy (RT) would benefit patients with advanced Hodgkin lymphoma (HL) with small tumors following chemotherapy. The authors found that RT may increase patients’ survival without worsening of HL, although this may also increase side effects. Some background Treatment options for patients with...Read More