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Does reduced intensity conditioning hematopoietic stem cell transplantation improve the outcomes of patients with chronic lymphocytic leukemia and Richter’s transformation?

Does reduced intensity conditioning hematopoietic stem cell transplantation improve the outcomes of patients with chronic lymphocytic leukemia and Richter’s transformation?

Posted by on Sep 19, 2021 in Leukemia | 0 comments

In a nutshell The study aimed to investigate whether reduced-intensity conditioning (RIC) hemopoietic stem cell transplantation (HSCT) improves the outcomes of patients with chronic lymphocytic leukemia (CLL) with and without Richter's transformation (RT).  This study concluded that this treatment may be suitable in early...

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Looking for patients to try a treatment combination for untreated chronic lymphocytic leukemia.

Posted by on May 28, 2019 in Leukemia | 0 comments

In a nutshell This study is searching for patients with previously untreated chronic lymphocytic leukemia (CLL) to try a new treatment combination containing obinutuzumab (Gazyva) or obinutuzumab/bendamustine (Treanda) to shrink the tumor (debulking) before treatment with venetoclax (Venclexta). The main outcome that will be measured is the number...

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Combining obinutuzumab and bendamustine for chronic lymphocytic leukemia patients

Combining obinutuzumab and bendamustine for chronic lymphocytic leukemia patients

Posted by on Jun 23, 2018 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the effectiveness of an obinutuzumab and bendamustine combination in chronic lymphocytic leukemia patients. This study concluded that this combination appears to be effective in these patients and has manageable side effects. Some background Obinutuzumab (Gazyva) is a monoclonal antibody. Monoclonal...

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Looking for patients with untreated chronic lymphocytic leukemia to test an ibrutinib and fludarabine treatment

Posted by on Sep 11, 2017 in Leukemia | 0 comments

In a nutshell This phase 2 clinical trial will test the safety and effectiveness of an ibrutinib (Imbruvica) and fludarabine (Fludara) treatment in patients with previously untreated chronic lymphocytic leukemia (CLL). The primary outcome will be measured by the safety and effectiveness of the treatment. The details Ibrutinib is a drug that...

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