In a nutshell This study investigated the survival outcomes of surgery in melanoma patients with metastasis in the abdominal organs (AV; spread to others internal organs such as liver, stomach etc). Researchers suggested that surgery is an important treatment option for these patients. Some background Surgery is an important treatment option...
Read MoreSite(s) of metastases-Other visceral organs (e.g. liver) Posts on Medivizor
Effectiveness of percutaneous hepatic perfusion in melanoma spread to liver
In a nutshell The authors evaluated the effect of percutaneous hepatic perfusion (PHP, a method of treating melanoma that has spread to the liver) with melphalan (Alkeran). This study found that PHP with melphalan improved outcomes in melanoma patients with cancer spread to the liver. Some background In advanced melanoma (stage 3/4), cancer...
Read MoreBenefits of surgery in advanced melanoma with liver metastasis
In a nutshell The authors evaluated melanoma patients with liver metastasis (spread of cancer from the skin to liver) undergoing surgery or other treatments. Some background In advanced melanoma (stage IV), cancer often spreads from the skin to the liver. There are two treatment options in liver metastasis – surgery and...
Read MoreChemotherapy in treating liver tumors caused by uveal melanoma
In a nutshell The authors aimed to determine the effect of hepatic intra-arterial (HIA) compared to intravenous (IV) fotemustine (Muphoran) treatment in patients with liver tumors from uveal melanoma. Some background Uveal melanoma is a rare form of cancer that occurs in the eye. In 5% of patients this will lead to cancer spread into other parts...
Read MoreIs liver-targeted chemotherapy effective?
In a nutshell This phase II clinical trial assessed the efficacy of a treatment called isolated hepatic perfusion (IHP) for the treatment of patients with liver metastases from ocular melanoma. Some background Ocular (uveal) melanoma is cancer of the pigmented cells (called melanocytes) of the eye. Although most patients undergo successful...
Read MoreDabrafenib increases progression-free survival in patients with metastatic melanoma with BRAF mutations
In a nutshell This phase 3 clinical trial compared the safety and efficacy of dabrafenib to a standard treatment for melanoma, dacarbazine in patients with metastatic melanoma. Some background BRAF is a protein that helps cells grow and multiply. A genetic defect can cause the BRAF protein to malfunction (BRAF mutation). A BRAF mutation is...
Read More
