Site(s) of metastases-Brain Posts on Medivizor
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Site(s) of metastases-Brain Posts on Medivizor

Salvage stereotactic radiosurgery in patients with breast cancer that has spread to the brain

Posted by on Mar 22, 2019 in Breast cancer | 0 comments

In a nutshell This study wanted to analyze the outcomes of patients with breast cancer that has come back into the brain and who needed salvage radiotherapy to the brain. The study found that performing radiotherapy on the brain was effective in controlling the cancer in these patients.   Some background Breast cancer can often spread...

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Effect of cancer medications nivolumab and ipilimumab on melanoma which has spread to the brain

Posted by on Sep 15, 2018 in Melanoma | 0 comments

In a nutshell This study looked at two medications for treatment of melanoma, nivolumab (Opdivo) and ipilimumab (Yervoy), and analysed how well they worked in patients who have melanoma which has spread to the brain. The study found that the combination of nivolumab and ipilimumab had significant clinical benefit in patients with melanoma with brain...

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Have targeted therapies improved the survival of patients with melanoma brain metastases

Posted by on Jun 28, 2018 in Melanoma | 0 comments

In a nutshell This study investigated whether the risk of developing melanoma brain metastases (MBM) and survival among patients with MBM has changed since the introduction of more effective therapies. The results found the overall survival for patients with MBM has improved significantly since 2011. Some background In more than 33% of patients...

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Searching for breast cancer patients with brain metastases to test a new chemotherapy drug

Posted by on Oct 30, 2017 in Breast cancer | 0 comments

In a nutshell This phase 3 trial aims to compare an investigational drug to standard chemotherapy in breast cancer patients with brain metastases. The main outcome to be investigated is overall survival (time from treatment until death from any cause). Another outcome to be measured is progression free survival (time from treatment until disease...

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Looking for patients to test the effectiveness lorlatinib in treating ALK or ROS1 positive non-small cell lung cancer

Posted by on Sep 26, 2017 in Lung cancer | 0 comments

In a nutshell This phase 2 trial will clinical trial will test the effectiveness of lorlatinib in treating non-small cell lung cancer (NSCLC) with anaplastic lymphoma kinase (ALK) and ROS proto-oncogene 1 (ROS1) mutations. The primary outcome will be measured by the rate at which the disease spreads to the central nervous system (CNS).   The...

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Looking for patients with non-small cell lung cancer to test the effectiveness of ceritinib in treating brain metastases

Posted by on Jul 11, 2017 in Lung cancer | 0 comments

In a nutshell This phase 2 clinical trial will test the effectiveness of ceritinib (Zykadia) treatment, in treating ALK positive non-small cell lung cancer (NSCLC) with brain metastases and/or leptomeningeal carcinomatosis. The primary outcome will be measured by the disease response to treatment. The details Some lung cancers are associated...

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Vemurafenib is an effective treatment option for BRAF-mutant metastatic melanoma

Posted by on Mar 6, 2017 in Melanoma | 0 comments

In a nutshell This study examined the effectiveness and safety of vemurafenib (Zelboraf) as treatment for BRAF-mutant metastatic melanoma. Researchers concluded that vemurafenib is an effective treatment option for patients with BRAF-mutated melanoma and brain metastasis (BM; spread to the brain). Some background Over 40% of melanoma patients...

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Treatment options for melanoma with brain metastasis

Posted by on Jan 24, 2016 in Melanoma | 0 comments

In a nutshell The authors reviewed different treatment options for melanoma that spread to brain. This included surgery and combination treatment, among others, and scope for future treatments.  Some background In advanced melanoma, the cancer often spreads to the brain. This is called brain metastasis. This affects quality of life and also...

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