In a nutshell This study looked at the treatment of type 2 diabetes with either daily or weekly insulin injections. They found that weekly insulin was as safe and effective as daily injections. Some background Glycated hemoglobin (Hba1c) is a measurement of how well a person’s blood sugars are controlled over a 3 month period. This is...
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In a nutshell This study is evaluating the effect of medically tailored meals and nutrition education via tele-health for patients with uncontrolled type 2 diabetes (T2D). The outcomes include changes in blood glucose control, body weight, and confidence in self-managing care. This study is taking place in Philadelphia, Pennsylvania, United...
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In a nutshell This study compared patients with type 2 diabetes (T2D) switching to either insulin glargine 300 (Toujeo) or insulin glargine 100 (Lantus). It found that both types of insulin glargine improved blood glucose control, and insulin glargine 300 had a lower risk of hypoglycemia (dangerously low blood glucose levels) outside of a clinical...
Read MoreIn a nutshell This article looked at the effectiveness of dulaglutide (Trulicity) compared to insulin glargine (Lantus) for patients with uncontrolled type 2 diabetes (T2D). This study concluded that dulaglutide is more effective for these patients compared to insulin glargine. Some background Metformin is recommended as a first-line treatment for...
Read MoreIn a nutshell This study evaluated empagliflozin (Jardiance) and linagliptin (Tradjenta) for the treatment of Type 2 diabetes (T2D). This study found that combining both drugs (Glyxambi) was more effective at lowering blood glucose levels than either medication alone, with similar side effects. Some background For patients with T2D, the...
Read MoreIn a nutshell This study evaluated the safety and effectiveness of a combination treatment between sodium-glucose cotransporter 2 (SGLT) inhibitors and glucagon-like peptide 1 (GLP1) receptor agonists for patients with Type 2 diabetes (T2D). This study concluded that combination treatment improved blood glucose control and reduced weight loss for...
Read MoreIn a nutshell This study evaluated whether adding vildagliptin (Galvus) to metformin (Glucophage) could improve the duration of blood glucose control for patients with newly diagnosed Type 2 Diabetes (T2D). The authors found that this treatment combination improved long-term blood glucose control for these patients. Some background...
Read MoreIn a nutshell This study compared the safety and effectiveness of oral semaglutide with liraglutide administered via subcutaneous (under the skin) injection in patients with type 2 diabetes (T2D). The authors concluded that both treatments were similarly safe and effective in these patients. Some background Glucagon-like-peptide-1 (GLP1)...
Read MoreIn a nutshell This study evaluated the impact of long-term pioglitazone (Actos) treatment on outcomes for patients with type 2 diabetes (T2D) taking insulin. The authors concluded that this treatment lowered mortality risk for these patients. Some background As T2D progresses, more intensive treatment may be required. Typically, this means increasing...
Read MoreIn a nutshell This study is investigating the safety and effectiveness of the EndoBarrier system for patients with poorly controlled type 2 diabetes (T2D) and obesity. The main outcome to be measured will be the change in blood glucose levels. This trial is recruiting in multiple locations across the United States. The details Bariatric surgery is the...
Read MoreIn a nutshell This study compared IDegLira (Xultophy) to insulin degludec (Tresiba) or liraglutide (Victoza) alone in patients with uncontrolled Type 2 diabetes (T2D). The authors concluded that combined IDegLira was more effective and had fewer side effects than either insulin medication alone. Some background One of the main...
Read MoreIn a nutshell This study is comparing the effectiveness of two different doses of semaglutide (Ozempic) in patients with Type 2 diabetes (T2D). The main outcome to be measured will be the change in HbA1c (average blood glucose levels over 3 months). The details One of the goals of treatment for patients with T2D is to improve glycemic (blood...
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