In a nutshell This study investigated sperm selection techniques in couples undergoing assisted reproduction (AR). They found that the choice of sperm selection techniques should be based on female age. Some background Assisted reproduction (AR) is used to help infertile couples. Male infertility (MI) is the cause in 30-50% of cases. MI can...
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In a nutshell This study examined if sperm quality affected the results of in vitro fertilization (IVF) in couples experiencing infertility. The results showed that higher sperm quality increased the chance of IVF success if few eggs were harvested. Some background IVF is a procedure where an egg is fertilized by a sperm in a dish. In cases...
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In a nutshell This study looked at routine variations in timing during intracytoplasmic sperm injection (ICSI). It found that changes in timing may affect egg quality, but did not alter pregnancy outcomes. Some background ICSI is an infertility treatment in which a single sperm cell is injected into the oocyte (egg). ICSI is most commonly used for...
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In a nutshell This study looked at mini-incision micro-dissection testicular sperm extraction, a modified surgery to collect sperm. It found that this was a useful procedure for men who do not produce enough sperm and that it may be less invasive than other surgeries. Some background Non-obstructive azoospermia (NOA) is a condition in which a man...
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In a nutshell This study looked at how methods used to prepare the womb lining affect the success of frozen embryo transfers. This study found that mild ovary stimulation was associated with better pregnancy outcomes compared to an artificial cycle. Some background In vitro fertilization (IVF) is an infertility treatment where the eggs...
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In a nutshell This study looked at whether blood levels of the HCG hormone affect the chances of pregnancy after in vitro fertilization (IVF). This study concluded that having high HCG levels in the blood was associated with a higher chance of pregnancy. Some background IVF is an infertility treatment in which eggs are removed from a...
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In a nutshell This article reviewed treatment options for patients with unexplained fertility (UEI). Some background UEI is the inability to conceive without a known cause or reason. UEI can affect as many as 50% of couples experiencing infertility. In this case, common causes of infertility in both men and women have been ruled...
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In a nutshell This phase 3 trial will investigate a new drug FE 999049 for the treatment of infertility. The main outcome will be the ongoing pregnancy rate. The details There are several steps in the treatment of infertility. The first step involves harvesting eggs or oocytes. Once oocytes are harvested, in vitro fertilization (IVF) or...
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In a nutshell This study examined the alcohol consumption of females and males prior to undergoing assisted reproduction, to determine if it negatively impacted the chances of a live birth. This study did not reveal any association between alcohol consumption and the likelihood of achieving a live birth following assisted reproduction. Some...
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In a nutshell This study explored the option of using low-dose human chorionic gonadotropin (hCG) alone to complete follicle maturity in natural cycle in vitro fertilization (IVF). The results showed that hCG alone could be used to complete follicle maturity. There was no requirement for follicle stimulating hormone (FSH). Some background...
Read MoreIn a nutshell This study examined whether blockage of tubes that transport sperm in men affects live birth rate. Some background Infertility, or the inability to conceive, affects 5-15% of couples worldwide. Conception requires the production of functional sperm and seminal fluid (fluid that holds sperm cells), transport of the semen through...
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In a nutshell This paper evaluates the effects of berberine compared to metformin in women with polycystic ovary syndrome who undergo IVF treatment. Some background Polycystic ovary syndrome causes infertility, an excess of androgen (male sex hormone) and anovulation (eggs not released from the...
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