In a nutshell This study investigated if the interpregnancy interval (IPI; the time between pregnancies) has an effect on the following pregnancy. They found that an IPI of less than 12 months or greater than 60 months is associated with worse pregnancy outcomes. Some background The interpregnancy interval (IPI) is the time between the end of one...
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In a nutshell This study investigated if dexamethasone (Ozurdex) improves the success of in vitro fertilization (IVF) in patients with elevated progesterone. They found that low-dose dexamethasone resulted in a higher birth rates following IVF. Some background During fertility treatment, women may undergo ovarian stimulation to...
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In a nutshell This study investigated the success rates of in vitro fertilization (IVF) following either frozen or fresh embryo transfer. They found that frozen-thawed embryo transfer resulted in higher pregnancy and birth rates. Some background To treat infertility embryos are artificially fertilized using techniques such as in vitro...
Read MoreIn a nutshell The aim of this phase 4 trial is to assess if a single dose of a gonadotrophin-releasing hormone (GnRH) agonist enhances implantation during in vitro fertilization (IVF). The main outcome to be measured is the rate of live births. This study is being conducted in New Jersey, in the United States. The details In very early pregnancy,...
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In a nutshell This study investigated if the utrogestan and hMG protocol improved the viability of embryos and success of IVF in women with PCOS. Some background Polycystic ovarian syndrome (PCOS) is a condition due to hormonal imbalances which results in irregular ovulation and mentruation and can greatly impact female fertility. In vitro...
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In a nutshell This trial aims to determine if sperm selection through microfluidic sperm sorting can improve embryo quality. The outcome to be measured is the proportion of high quality embryos on day 3. This trial is located in San Francisco (California), United States. The details In-vitro fertilization (IVF) is a procedure whereby the...
Read MoreIn a nutshell This trial aims to see how the timing of triggering the release of the eggs in IVF may affect fertility outcomes. The main outcomes to be investigated are the percentage of normal embryos, mature eggs, and live birth rate. The trial is recruiting in Colorado, USA. The details In-vitro fertilisation (IVF) is a procedure where the...
Read MoreIn a nutshell This paper compared individualized versus conventional ovarian stimulation in women undergoing in-vitro fertilization (IVF). Authors concluded that individualized dosing for ovarian stimulation is as efficient and safer than conventional ovarian stimulation. Some background IVF is a procedure where the sperm fertilizes the egg in a...
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In a nutshell This study compared progesterone injections with vaginal administration in women undergoing assisted reproductive techniques. Authors reported no significant differences across modes of administration in pregnancy rates, live birth rates, or complications. Some background The hormone progesterone is important for the successful...
Read MoreIn a nutshell This study investigated the effects of a low calorie, low-glycemic index (a measure of the effect carbohydrate foods have on blood sugar hormone levels) diet on pregnancy rates in overweight women with infertility. The study showed that a low glycemic diet led to decreased weight and improved pregnancy rates. Some...
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In a nutshell This study examined the use of medroxyprogesterone acetate in the prevention of unwanted hormonal increase during fertility treatment. Some background In-vitro fertilization (IVF) is when a male sperm fertilizes the females’ egg in a laboratory dish outside the body, and is implanted into the woman's uterus....
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In a nutshell This article looks at sperm DNA fragmentation and if this influences assisted reproduction outcomes in women with different ovarian reserves. Some background Assisted reproduction techinques include in-vitro fertilization and intra-cytoplasmic sperm injection. In-vitro fertilization (IVF) is when a male sperm fertilizes...
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