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Performance status-3 – Symptomatic, 50 in bed Posts on Medivizor

Looking for patients with multiple myeloma to try a maintenance therapy combination after SCT

Posted by on Sep 30, 2019 in Multiple Myeloma | 0 comments

In a nutshell This trial will compare the effectiveness of two maintenance therapies in patients with multiple myeloma (MM) after a stem cell transplant (SCT). The main outcome to be measured will be the average time from treatment until death due to any cause.  The details Maintenance therapy is commonly given after SCT to help delay...

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Evaluating a new CAR-T cell therapy for patients with relapsed or refractory multiple myeloma

Posted by on Mar 10, 2019 in Multiple Myeloma | 0 comments

In a nutshell This study investigated the safety and effectiveness of a new chimeric antigen receptor (CAR) T cell therapy for relapsed or refractory (does not respond to treatment) multiple myeloma (MM). This study found that this cell therapy was effective, but it had significant side effects.   Some background MM is a type of cancer of the...

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Should elderly patients with NSCLC be treated with less aggressive radiation therapy?

Posted by on Oct 26, 2017 in Lung cancer | 0 comments

In a nutshell This trial examined whether aggressive radiation would cause severe side effects in patients over 80 years old with early stage non-small-cell lung cancer (NSCLC). The authors concluded that SBRT is safe and tolerable for older patients. Some background Stereotactic body radiation therapy (SBRT) is a type of radiation that delivers...

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Dealing with cancer pain: Low-dose morphine examined

Posted by on Feb 6, 2016 in Breast cancer | 0 comments

In a nutshell This study compared weak opioids and low-dose morphine in providing pain relief for moderate cancer pain. Researchers concluded that low-dose morphine is more suitable as pain management for moderate cancer pain than weaker pain relievers. Some background The guidelines for cancer pain relief developed by the World Health...

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FDA approved drugs in the last 20 years for the treatment of Metastatic Breast Cancer

FDA approved drugs in the last 20 years for the treatment of Metastatic Breast Cancer

Posted by on Aug 31, 2014 in Breast cancer | 0 comments

The article reviews drugs that were approved by the US Food and Drug Administration (FDA) for the treatment of Metastatic Breast Cancer (MBC) in the last 20 years. The authors summarize the clinical studies which lead to FDA approval. ‘First-line therapy’ is the initial treatment used to reduce cancer burden. It is usually the standard...

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Can chemotherapy make inoperable cancer operable?

Can chemotherapy make inoperable cancer operable?

Posted by on Sep 29, 2013 in Colorectal cancer | 0 comments

In a nutshell This study investigated the benefits of chemotherapy to treat inoperable (that cannot be removed through surgery) metastases from colorectal cancer (CRC). Some background When CRC is discovered early, the preferred method of treatment is surgery to remove the cancer along with some surrounding healthy tissue. Chemotherapy is often...

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The benefit of adjuvant chemotherapy in the treatment of older patients with advanced colon cancer

Posted by on Aug 21, 2013 in Colorectal cancer | 0 comments

In a nutshell In this study, researchers examined how adjuvant chemotherapy benefits colon cancer patients over the age of 75. Some background Adjuvant chemotherapy (the addition of chemotherapy to another treatment, such as surgery) has been shown to benefit survival in multiple trials and is considered common practice for patients with advanced...

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Comparison between two radiation therapy schedules

Posted by on Aug 9, 2013 in Lung cancer | 0 comments

In a nutshell This trial compared the survival of lung cancer patients, between patients receiving standard radiation therapy and those receiving radiation therapy given on alternative schedules (hyperfractionated or accelerated). Some background This research was prompted by recent findings that suggest a benefit with hyperfractionated or...

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Evaluating the effects on survival of chemotherapy after surgery to remove liver or lung metastases in patients with colorectal cancer

Posted by on Jul 20, 2013 in Colorectal cancer | 0 comments

In a nutshell This article evaluated the effects of chemotherapy after the surgical removal of liver and lung metastases on survival in patients with colorectal cancer (CRC).  Some background Metastatic CRC is cancer that has spread from the large intestine to distant organs or tissues in the body. The parts of the body mainly affected by...

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Evaluating continuation of bevacizumab plus chemotherapy in patients with metastatic colorectal cancer after disease progression

Posted by on Jun 27, 2013 in Colorectal cancer | 0 comments

In a nutshell This article evaluated the use of bevacizumab alongside chemotherapy in patients with metastatic colorectal cancer after the progression of the disease following treatment with bevacizumab. Some background Cancer cells need blood supply in order to grow. They do so by forming new blood vessels thereby feeding...

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Are there any benefits to continuing trastuzumab after disease progression in patients with HER2+ metastatic breast cancer?

Posted by on Jun 25, 2013 in Breast cancer | 0 comments

In a nutshell This article evaluated the benefits of continuing trastuzumab treatment after disease progression in patients with HER2+ metastatic (spread to distant organs and tissues) breast cancer. Some background Breast cancer cells have on their surface some proteins called receptors. Hormones bind to these receptors causing changes in the...

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Evaluating the benefits of laparoscopy in determining the extent of peritoneal carcinomatosis for patients with colorectal cancer

Posted by on May 13, 2013 in Colorectal cancer | 0 comments

In a nutshell This article evaluated whether the use of a minimally invasive diagnostic technique called laparoscopy before surgery to treat peritoneal carcinomatosis improves the selection of patients who can benefit the most from treatment. The authors of the study found that laparoscopy can be used to select patients for whom surgery may be a...

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