In a nutshell This study evaluated the long-term relationship between bariatric surgery (BS; weight loss surgery) and major adverse cardiovascular events (MACE) in patients with obesity, diabetes, and hypertension (high blood pressure; BP). The study showed that a sustained decrease in MACE occurrence was associated with BS in these patients. Some...
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In a nutshell This study investigated the effects of glucagon-like peptide 1 receptor agonists (GLP-1Ra) in patients with diabetes. They found that GLP-1Ra drugs improved cardiovascular (CV), kidney and mortality outcomes. Some background Type 2 diabetes (T2D) is caused by a reduced response to insulin. This is called insulin...
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In a nutshell This study investigated ticagrelor (Brilique) added to aspirin in patients with coronary artery disease (CAD) and diabetes mellitus (DM). They found that ticagrelor reduced the risk of cardiac events in these patients. Some background Patients with diabetes have a higher risk of ischemic events (IEs). IEs are caused by a lack...
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In a nutshell This article investigated the safety and effectiveness of percutaneous coronary intervention with drug-eluting stent (PCI-DES) vs coronary artery bypass graft (CABG) for patients with diabetes mellitus (DM). The authors concluded that CABG was better than PC-DES in these patients. Some background DM is a disorder where the...
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In a nutshell This study investigated if metformin (Glucophage) improves left ventricular hypertrophy (LVH; enlargement of the left lower chamber of the heart) in coronary artery disease (CAD). They found that this treatment improved LVH and other CAD symptoms. Some background Coronary artery disease (CAD) is a disease of the...
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In a nutshell This study investigated whether the severity of chest pain (angina) affects the impact of different treatments for stable coronary artery disease (CAD) in people with type 2 diabetes (T2D). It was determined that those with more severe angina were more likely to need revascularization (PCI or CABG), and to have severe angina after...
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In a nutshell This study aimed to determine the timing of mortality and other non-fatal adverse events according to diabetic status and type of acute coronary syndrome (ACS). It was found that the type of ACS but not the diabetic status determines the timing of fatal and non-fatal adverse events. Some background Patients with diabetes mellitus...
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In a nutshell This phase II trial evaluated the benefit of a new drug of the aldosterone synthase inhibitors class in the treatment of high blood pressure. Different doses of this new drug were compared to a placebo, and the effects on blood pressure were reviewed. Some background Aldosterone is a hormone produced by the adrenal glands, and a key...
Read MoreIn a nutshell This study compared the outcomes of two interventional procedures for multivessel coronary artery disease, coronary artery-bypass grafting (CABG) and percutaneous coronary intervention (PCI) in patients with diabetes mellitus (DM). Some background Coronary artery disease (CAD) is a condition caused by the narrowing of the blood...
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In a nutshell This comprehensive rehabilitation trial evaluated the benefit, if any, of cardiac rehablitation on survival, cardiac or psychological wellness, and general well-being in heart attack survivors. Some background Myocardial Infarction(MI) or heart-attack occurs when flow of oxygen-rich blood is suddenly blocked from reaching the...
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In a nutshell The present study examined whether combining a healthy diet with medications has an added benefit on the risk of cardiovascular events, such as heart attacks and strokes . Some background Cardiovascular diseases (CVD) are conditions affecting the heart and/or blood vessels. Many medications, such as beta blockers,...
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