In a nutshell This study wanted to find out what put patients at risk of having immune-related side effects when they were treated with pembrolizumab (Keytruda). The study found that patients with a higher body mass index (BMI; a measurement of weight in relation to height) and more cycles of treatment were more likely to determine...
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In a nutshell This study wanted to find out if patients with melanoma who had immune system side effects after treatment with nivolumab (Opdivo) had better outcomes than patients without side effects. The study found that the patients who had side effects from using nivolumab ended up with better responses to treatment and...
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In a nutshell This study evaluated the long-term safety and effectiveness of cryoablation (a process that uses extreme cold to destroy tissue) for patients with early prostate cancer. This study found that cryoablation is safe and effective for early-stage prostate cancer. Some background Cryoablation is a treatment option for early-stage prostate...
Read MoreIn a nutshell The study looked at the use of FDG-PET imaging to assess long-term outcomes of treatment in patients with melanoma. Researchers found that FDG-PET imaging may be useful in predicting long-term outcomes of treatment in these patients. Some background Treatment for melanoma has vastly improved in recent years. Immunotherapies have improved...
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In a nutshell This study looked at the safety and effectiveness of pembrolizumab (Keytruda) and ipilimumab (Yervoy), in the treatment of patients with advanced melanoma. The authors found that overall survival was higher in the group treated with pembrolizumab in all cases. Some background Cancer cells can have different receptors for certain...
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In a nutshell This study aimed to compare lapatinib (Tykerb) and trastuzumab (Herceptin) in patients with HER-2 receptor positive breast cancer. This study found that in patients with hormone receptor-positive tumors, use of lapatinib for 6 months, followed by trastuzumab for 12 months significantly improved survival...
Read MoreIn a nutshell The study examined if age played a role in the effect of immunotherapy treatment on patients with melanoma. The study concluded that immunotherapy is similarly effective in patients of all ages. Some background Immunotherapy is a type of treatment which targets the immune system to help it to fight cancer. A specific type of...
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Video information: In this replay, medical oncologist/melanoma specialist Dr. Michael Postow joins Patient Power host Andrew Schorr online from Memorial Sloan Kettering Cancer Center to discuss combination therapies for patients with advanced melanoma. In the online chat, Andrew and Dr. Postow discuss how patients can get life-extending treatments...
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In a nutshell This study investigated the effects on the immune system associated with the use of ipilimumab (Yervoy) to treat melanoma. Researchers suggested that one-third of the patients treated with ipilimimuab required treatment for the negative side effects. Some background Ipilimumab is an antibody that helps the immune system to...
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In a nutshell This study investigated the negative effects on the skin associated with the use of nivolumab (Opdivo) to treat melanoma. Researchers suggested that skin complications are the most frequent side effects but they are in most cases manageable. Some background The use of PD-1 antibodies, such as nivolumab (Opdivo) or pembrolizumab...
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In a nutshell The authors reviewed the treatment-related side effects associated with ipilimumab (Yervoy), pembrolizumab (Keytruda), and nivolumab (Opdivo) in melanoma. The authors found that a higher dose of ipilimumab was correlated with more side effects, but the same was not true for pembrolizumab and nivolumab. Some background In advanced...
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In a nutshell The authors compared the safety and effectiveness of pembrolizumab (Keytruda) to chemotherapy for the treatment of ipilimumab (Yervoy)-resistant melanoma. Some background Ipilimumab, an immunotherapy (treatment that uses the body’s own immune system to fight cancer), is an approved drug for the...
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