In a nutshell This study evaluated whether liraglutide (Victoza) improves diabetic control in patients with difficult to control type 2 diabetes (T2D) and if there were certain factors that influence the effects of liraglutide. It found that patients responded equally well to liraglutide regardless of body mass index (BMI; a measurement of...Read More
Non-insulin oral drug(s)-Glucophage (Metformin) Posts on Medivizor
In a nutshell This study explored the effects of different second-line therapies combined with metformin (Glucophage) in patients with type 2 diabetes (T2D). The data showed that metformin combinations with a sulfonylurea (SU) had the lowest weight loss, the smallest effect of lowering blood glucose, and an overall, reduced health...Read More
Improved outcomes with linagliptin in patients with persistent prediabetes after metformin and lifestyle modifications.
In a nutshell This study evaluated the addition of linagliptin (Trajenta) to metformin (Glucophage) and lifestyle changes in patients with persistent prediabetes. The authors concluded that adding linagliptin after 12 months of metformin treatment and lifestyle changes improved glucose levels and pancreatic β-cell function in these...Read More
Comparing metformin extended-release to metformin immediate-release for adults with type 2 diabetes.
In a nutshell This study compared the effectiveness and tolerance of metformin (Glucophage) extended-release (MXR) and conventional metformin immediate-release (MIR) in adults with type 2 diabetes (T2D). The authors concluded that MIR had better glucose control while MXR but reduced gastrointestinal (GI) side effects. Some background...Read More
Is treatment with pioglitazone and exenatide more effective than insulin for poorly controlled type 2 diabetes?
In a nutshell This study compared a combination of pioglitazone (Actos) and exenatide (Byetta) to insulin therapy for poorly controlled type 2 diabetes (T2D). It found that more patients receiving pioglitazone and exenatide achieved blood glucose control compared to those receiving insulin. Some...Read More
Is combination treatment with exenatide and dapagliflozin safe and effective for poorly-controlled type 2 diabetes?
In a nutshell This study looked at the treatment of poorly-controlled type 2 diabetics. They found that a combination of exenatide and dapagliflozin was more effective at lowering blood glucose (sugar) than either treatment alone. Some background There are many types of treatment for type 2 diabetes (T2D). Metformin (Glucophage) is commonly...Read More
You may not realize it but your diabetes medication, metformin extended release, has been recalled. One of the places to look for information on recalls of medications is the Recalls, Market Withdrawals, & Safety Alerts page on the FDA website. The recall, on May 28, is for Metformin Hydrochloride Extended-Release Tablets, USP 500mg by a...Read More
In a nutshell This study compared the safety and effectiveness of semaglutide (Ozempic) and canagliflozin (Invokana) for patients with uncontrolled type 2 diabetes (T2D). The authors found that semaglutide more effectively reduced blood glucose levels and body weight than canagliflozin. Some background Often, patients with T2D are given...Read More
In a nutshell This article investigated the safety and effectiveness of triple therapy with low dose dapagliflozin (Farxiga) plus saxagliptin (Onglyza) added to metformin (Glucophage) in uncontrolled type 2 diabetes (T2D). The authors concluded that triple therapy significantly improved blood glucose control in these patients. Some background T2D...Read More
In a nutshell This study investigated if metformin (Glucophage) improves left ventricular hypertrophy (LVH; enlargement of the left lower chamber of the heart) in coronary artery disease (CAD). They found that this treatment improved LVH and other CAD symptoms. Some background Coronary artery disease (CAD) is a disease of the...Read More
In a nutshell This article investigated the safety and effectiveness of higher doses of dulaglutide (Trulicity) in the management of type 2 diabetes (T2DM) in patients on metformin (Glucophage). The authors concluded that the higher doses of dulaglutide are effective and safe in these patients. Some background In T2DM the...Read More
In a nutshell The aim of this study was to compare the effects of adding semaglutide versus sitagliptin onto metformin with or without a sulfonylurea in type 2 diabetes (T2D). The main finding was that adding 7mg or 14mg semaglutide on to metformin/sulphonylurea therapy showed greater improvements in blood sugar control compared to sitagliptin. Some...Read More