Menopausal status-Postmenopausal Page 2 Posts on Medivizor
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Menopausal status-Postmenopausal Posts on Medivizor

The benefits of melatonin on sleep disturbances in women with breast cancer

Posted by on Sep 15, 2015 in Breast cancer | 0 comments

In a nutshell The authors aimed to determine whether or not a hormone called melatonin could positively influence the quality of life of women with breast cancer. Some background Sleep disturbance is common among women with breast cancer. Melatonin is a hormone that induces sleepiness. This hormone is naturally found in our body but may decrease...

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Aromatase inhibitor treatment is associated with metabolic changes in the brain

Posted by on Dec 28, 2014 in Breast cancer | 0 comments

In a nutshell This paper studied the effect of aromatase inhibitors on cognitive function of older patients with breast cancer.  Some background Aromatase inhibitors are drugs that block the activity of estrogen receptors (proteins on cells that react to the presence of the hormone estrogen). Not only do estrogen receptors promote cell growth...

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Everolimus and adverse events

Posted by on Sep 29, 2014 in Breast cancer | 0 comments

In a nutshell This paper reviewed adverse events associated with treatment of breast cancer with everolimus (Afinitus). Some background Everolimus is used in postmenopausal patients for advanced breast cancer treatments. The drug has been approved for use in patients with hormone receptor positive (the presence of the estrogen...

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Anastrozole and letrozole are associated with equal rates of side effects

Posted by on Aug 3, 2013 in Breast cancer | 0 comments

In a nutshell Researchers compared therapy with anastrozole (arimidex) and letrozole (femara) to determine the effects of these drugs on the quality of life (QoL) of breast cancer patients. Some background In the case of hormone receptor positive (HR+) breast cancer, patients typically receive surgery, followed by adjuvant (additional) treatment...

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Phase II clinical trial testing the safety and efficacy of adding entinostat to exemestane therapy in hormone-resistant breast cancer patients

Posted by on Jun 5, 2013 in Breast cancer | 0 comments

In a nutshell This phase II clinical trial tested whether a new drug, entinostat, can work in concert with exemestane (a hormone therapy drug), to fight breast cancer that no longer responds to hormone therapy alone. Some background Some breast cancers need estrogen (a female sex hormone) to grow. These breast cancer cells respond to estrogen via...

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Phase 3 clinical trial evaluating the safety and efficacy of adding everolimus to exemestane therapy in patients with hormone receptor-positive advanced breast cancer

Posted by on Jun 1, 2013 in Breast cancer | 0 comments

In a nutshell This phase 3 clinical trial tested whether everolimus (a non-hormonal treatment) added to hormone therapy with exemestane improved survival in patients with advanced breast cancer (BCa).  Some background Some BCa are fueled by female sex hormones (estrogen or progesterone) that help them grow. These types of cancer are called...

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Combination of Anastrozole and Fulvestrant therapy in hormone receptor positive metastatic breast cancer

Posted by on Apr 29, 2013 in Breast cancer | 0 comments

In a nutshell This study compared the effect of two regimens for hormone-positive, metastatic breast cancer on disease progression and survival: a combination of two drugs, namely anastrozole (Arimidex) and fulvestrant (Faslodex), versus anastrozole alone.  Some background Breast cancers often require estrogen (the female sex...

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Benefits of postoperative chemotherapy vary according to breast cancer type

Posted by on Feb 25, 2013 in Breast cancer | 0 comments

In a nutshell This study questioned the benefit of adding chemotherapy to postoperative hormonal treatment in the case of lobular breast cancer. Their findings were that chemotherapy seems to offer no additional beneficial effects in women with lobular breast cancer receiving hormonal therapy. Some background There are two main types of breast...

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