In a nutshell This paper studied the effectiveness of Leining in treatment of patients with rheumatoid arthritis. Some background Methotrexate (Trexall, Rheumatrex) is used to treat rheumatoid arthritis. However, not all patients have an optimal response to methotrexate. Abatacept (Orencia) is an effective and...
Read More
In a nutshell This study examined whether a combination of methotrexate and tumor-necrosis factor inhibitors was more effective in treatment of rheumatoid arthritis than methotrexate alone. Some background Rheumatoid arthritis is a chronic (long-term) disease, therefore the focus of treatment is to prevent joint damage and slow the progression of...
Read More
In a nutshell This study examined the safety and efficacy of sirukumab in the treatment of rheumatoid arthritis. Some background Inflammation is a major factor in rheumatoid arthritis, leading to joint pain and swelling. Interleukin-6 is a protein involved with inflammation, and is elevated in rheumatoid arthritis patients. Therefore,...
Read More
In a nutshell This study reported the 2-year outcomes of a previous trial of conventional (addition of sulfasalazine and hydroxychloroquine) versus biological (addition of infliximab) treatment in patients who failed initial methotrexate treatment. Some background Rheumatoid arthritis (RA) is a chronic inflammatory disease that typically...
Read More
In a nutshell This study evaluates the outcomes associated with 2 years of treatment with rituximab + methotrexate versus methotrexate alone in rheumatoid arthritis patients. Some background Rheumatoid arthritis (RA) is a chronic inflammatory disease that typically affects the small joints in the hands and feet. It is an autoimmune disorder,...
Read More
