In a nutshell This article reviewed treatment guidelines that have been recommended for patients with early-stage prostate cancer. Some background This analysis of existing treatment guidelines was done by the leading experts in prostate cancer research. They have made recommendations on the treatment of early-stage prostate cancer. Methods...
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In a nutshell This study investigated the outcomes of chemotherapy before surgery in patients with high-risk rectal cancer. Researchers suggested that chemotherapy improves tumor shrinkage before rectal surgery. Some background The standard treatment for patients with rectal cancer is surgery. High-risk patients may benefit from short-course...
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In a nutshell This trial is examining the effectiveness of tesetaxel plus a reduced dose of capecitabine for hormone receptor (HR) positive/HER2 negative advanced breast cancer. The main outcome to be measured will be progression free survival (time from treatment until disease progression). The details Breast cancer is classified into...
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In a nutshell This study investigated the safety of the chemotherapies mFOLFOX6 and XELOX in Japanese colon cancer patients. Researchers suggested that the safety of both treatments is acceptable. Some background FOLFOX chemotherapy is the standard treatment for stage 3 colon cancer patients who underwent surgery. mFOLFOX6 combines leucovorin,...
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In a nutshell This study investigated if sentinel lymph node (SLN) status was linked to Breslow thickness in understanding the prognosis of melanoma (a type of skin cancer). The study concluded that SLN status was not linked to Breslow thickness (BT) for melanoma prognosis. Some background Sentinel lymph nodes...
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In a nutshell This study investigated the effectiveness of pembrolizumab (Keytruda) in the treatment of patients with stage 3 melanoma who underwent surgery. Researchers suggested that this drug is associated with longer recurrence-free survival with no new side effects. Some background The use of PD-1 antibodies, such as pembrolizumab, in patients...
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In a nutshell This study looked at the impact of cachexia (weakness or wasting of the body) in elderly patients with advanced non-small-cell lung cancer on disability, hospitalization and medical costs. The authors concluded that patients with cachexia had a higher risk of disability, longer hospital stays and higher medical costs, while being treated...
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In a nutshell This study aimed to discover if docetaxel (Taxotere) added to androgen-deprivation therapy (ADT) increases overall survival for patients with metastatic hormone-sensitive prostate cancer. This study found that overall survival was higher for patients who received ADT and docetaxel compared to those who took ADT. Some...
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In a nutshell This study examined improvement in treatment related menopausal symptoms in patients who have had breast cancer and eat a diet rich in soy or cruciferous vegetable. This study found that higher soy and cruciferous vegetable intake was associated with less treatment-related menopausal symptoms and fatigue. Some background...
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In a nutshell This study examined the side effects and health related quality of life (HRQL) of advanced melanoma patients treated with cobimetinib (Cotellic) plus vemurafenib (Zelboraf). Researchers suggested that these patients maintained their HRQL when compared with patients treated with vemurafenib alone. Some background Prior studies...
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In a nutshell This study examined the incidence of pleural effusion in lung cancer patients after treatment with thoracic radiation therapy and identified risk factors associated with it. They concluded that patients treated with 5 Gy of radiation to over 41.5% of the lung were at the greatest risk of developing pleural effusion after treatment. Some...
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In a nutshell This study aimed to examine the links between prostate specific antigen (PSA, a protein present in prostate cancer) and survival in patients with metastatic castration-resistant prostate cancer treated with cabazitaxel. This studty concluded that PSA response after cabazitaxel treatment is associated with improved...
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