In a nutshell This study aimed to investigate if rituximab (Rituxan), bendamustine (Treanda), and mitoxantrone (Novantrone) or R-BM followed by rituximab consolidation was a safe and effective treatment in older patients with follicular lymphoma (FL). The authors concluded that this treatment provided durable responses and was well tolerated in...Read More
Current stage-Stage I (Early) Posts on Medivizor
The effectiveness of chemotherapy and radiotherapy in nodular lymphocyte predominant Hodgkin lymphoma depending on disease stage
In a nutshell This study aimed to investigate the effectiveness of chemotherapy and radiotherapy (CRT) in patients with nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL). This study concluded that combined CRT may be more effective in patients with early-stage NLPHL, particularly in older patients. Some background...Read More
In a nutshell This study aimed to compare autologous stem cell transplant (ASCT) and conventional chemotherapy (CT) as second-line treatments in patients with relapsed early-stage (ES), classical Hodgkin lymphoma (cHL). This study concluded that CT treatments may be a suitable second-line treatment option for patients...Read More
In a nutshell This trial is looking to assess the effectiveness of ME-401 for relapsed follicular lymphoma (FL) after the failure of two or more therapies. The main outcome to be measured in this trial is the percentage of patients whose cancer shrinks or disappears after treatment. The details FL is a type of non-Hodgkin lymphoma....Read More
Does tumor size affect long-term outcomes after treatment for patients with early-stage Hodgkin lymphoma?
In a nutshell This study evaluated whether tumor size affected treatment outcomes for patients with early-stage (ES) Hodgkin lymphoma (HL). This study concluded that the risk of cancer recurrence increased with increasing tumor size. Some background PET scanning during treatment is used to guide therapy for patients with HL. Depending on the scan...Read More
Is radiotherapy after chemotherapy associated with late side effects in patients with Hodgkin’s lymphoma?
In a nutshell This study evaluated the long-term outcomes of chemotherapy plus radiotherapy for patients with early-stage classical Hodgkin's lymphoma (cHL). The authors found that this treatment combination was highly effective, with minimal late side effects. Some background Early-stage (stage 1 to 2) cHL is usually treated with a...Read More
In a nutshell This study evaluated whether PET scanning after chemotherapy might help predict outcomes and guide treatment for patients with early-stage Hodgkin's lymphoma (HL). This study found that PET scanning can help identify high-risk patients after chemotherapy. Some background Chemotherapy combined with radiotherapy is the standard of...Read More
In a nutshell This study evaluated the effectiveness and safety of a modified chemotherapy regimen for patients with early-stage Hodgkin lymphoma (HL). This study concluded that this regimen was effective but associated with more side effects. Some background The most commonly used frontline chemotherapy regimen for HL is ABVD (doxorubicin,...Read More
In a nutshell This trial will evaluate the effects of a new treatment parsaclisib (INCB050465) in relapsed or unresponsive follicular lymphoma (FL). Response rate, survival, and side effects will be the main outcomes measured. The details Many patients are cured with treatments for follicular lymphoma (FL). Some, however, lose response to therapy...Read More
In a nutshell This study investigated the long-term survival outcomes of patients with stage 1 non-Hodgkin’s lymphoma (NHL). This study concluded that these patients have favorable outcomes but may need follow-up after 5 years of remission (no cancer recurrence). Some background Most patients with early-stage (stage 1 – 2) NHL tend to have...Read More
In a nutshell This study investigated the development of Hodgkin lymphoma (HL) above and below the diaphragm. Patients with HL above the diaphragm had better survival and response to treatment. Some background HL is a type of cancer which affects the lymph nodes. HL may develop above or below the diaphragm (a muscle which helps you...Read More
In a nutshell This study investigated the effectiveness, side effects, and relapse patterns of patients with low-grade (indolent; painless) follicular lymphoma (FL) or marginal zone lymphoma (MZL) after low-dose radiotherapy (LDRT). This study concluded that LDRT is an effective treatment in patients with low-grade disease and a low tumor burden. Some...Read More