In a nutshell This study aimed to evaluate the use of testosterone replacement therapy (TRT) in men who had definitive treatment for prostate cancer. The authors concluded that TRT was not associated with a higher risk of recurrence in these patients. Some background Prostate cancer (PCa) is commonly fueled by the sex hormone testosterone....
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In a nutshell The authors determined the benefits and pitfalls of active surveillance (AS). The authors concluded that AS may reduce over-treatment in low-risk prostate cancer patients without compromising 10-year prostate cancer survival. Some background AS is a form of non-treatment used in prostate cancer patients who are low-risk. This...
Read MoreIn a nutshell This review examined predictors of disease progression in low-risk prostate cancer during active surveillance. Researchers concluded that certain blood markers, biopsy results, and ethnicity could help predict which patients were more likely to experience disease progression. Some background Active surveillance of prostate...
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In a nutshell The authors determined the association between perineural invasion (cancer on the nerves inside the prostate) and disease progression in men with prostate cancer on active surveillance (watchful waiting). Some background Active surveillance is common in early stage (stage I or II) prostate cancer. It involves actively...
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In a nutshell The authors determined the risk factors that led to disease reclassification (change in grade/status of the disease) in prostate cancer patients under active surveillance. Some background Active surveillance is common in early-stage prostate cancer management. It involves active monitoring of patients for any changes in symptoms or...
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In a nutshell The authors aimed to determine the effect of phosphodiesterase type 5 inhibitors on biochemical recurrence following prostate surgery. Some background Prostate surgery is a form of treatment that involves surgically removing the prostate gland which can cause erectile dysfunction in some patients. Phosphodiesterase type 5 inhibitors...
Read MoreIn a nutshell The authors aimed to determine the effects of weight in prostate cancer progression under active surveillance. Some background Active surveillance involves actively monitoring tumor growth and development in a patient without administering treatment. Prostate cancer patients undergoing active surveillance who have a high...
Read MoreIn a nutshell The authors aimed to determine long-term outcomes in prostate cancer patients following treatment with watchful waiting or prostate surgery. Some background In early prostate cancer, watchful waiting is a form of treatment that involves closely monitoring a patient to determine any signs of cancer progression, but does not involve...
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In a nutshell The authors aimed to determine whether African Americans underwent more frequent reclassifications than Caucasians on active surveillance. Some background Active surveillance involves close observation of the cancer to detect any signs of cancer progression rather than immediate treatment. This is typically carried out in...
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In a nutshell This report discusses using a device to track tumor sites in follow-up biopsies in prostate cancer. Some background Biopsies (the removal of tissue from the body and examination to establish the presence of cancer) are a very important part of active surveillance (patient monitoring instead of treatment) in early prostate...
Read MoreIn a nutshell This phase III trial is studying prostate radiation therapy to see how well it works compared with short-term androgen deprivation therapy given together with pelvic lymph node radiation therapy with or without prostate radiation therapy in treating patients with a rising prostate specific antien (PSA) after prostatectomy (surgery...
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In a nutshell This study evaluated the use of multi-parametric magnetic resonance imagining (MRI) in the selection of prostate cancer patients for active surveillance. Some background Active surveillance was introduced as a therapeutic strategy to avoid overtreatment of cancer patients with a relatively non-threatening disease. In active...
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