In a nutshell The authors aimed to determine whether hormone therapy had an effect on biochemical failure and cancer spread in prostate cancer patients undergoing radiation therapy. Some background Intermediate-risk prostate cancer is cancer that requires active treatment due to growth through and/or out of the prostate. It can be treated...
Read MoreIn a nutshell The authors aimed to determine the effect of common treatments on prostate cancer-specific mortality for patients with intermediate-risk prostate cancer. Some background Intermediate-risk prostate cancer is cancer that has grown through and/or out of the prostate. It can be further classified as favorable or...
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In a nutshell The authors aimed to determine the effect of orteronel in patients resistant to hormone treatment. Some background Hormone therapy is commonly used in prostate cancer treatment and involves targeting the male sex hormones active in prostate cancer, such as testosterone. In some cases patients receiving hormone therapy may become...
Read MoreIn a nutshell The authors aimed to identify the best options available to identify metastatic prostate cancer. Some background Metastatic prostate cancer is cancer that has spread from the prostate gland into tissues and organs around the body. In some cases patients with metastatic cancer can become resistant to certain treatments, such as...
Read MoreIn a nutshell The authors aimed to determine the impact of docetaxel on patient quality of life. Some background Metastatic cancer is cancer that has spread around the body from the primary tumor site. Docetaxel (Taxotere, Docecad) is a chemotherapy drug used to treat lung, prostate, breast, stomach and head/neck cancer by preventing cancer...
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In a nutshell The authors aimed to determine whether long-term hormone treatment was superior to short-term treatment when used with radiation therapy. Some background Radiotherapy and hormone therapy are common treatments used in prostate cancer patients. Radiotherapy involves directing a beam of radiation at the tumor site in order to kill...
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In a nutshell The authors reviewed the effect of androgen deprivation therapy in treating patients with advanced prostate cancer. Some background Androgen deprivation therapy (ADT) is a form of hormone treatment that targets the male sex hormones involved in prostate cancer, such as testosterone. ADT is the standard treatment for cancer that has...
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In a nutshell This paper investigates measurement of the levels of the protein prostate-specific-antigen (PSA) as a predictor of cancer returning when the patient is treated with neoadjuvant androgen deprivation therapy and radiotherapy. Some background Prostate cancer patients have been shown to have higher rates of biochemical relapse-free...
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In a nutshell This study evaluated long-term mortality with intermediate-risk prostate cancer and the significance of favorable versus unfavorable prognostic factors in the selection of the most appropriate therapy. Some background Men newly diagnosed with prostate cancer are initially stratified into three risk groups based on low, intermediate,...
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In a nutshell This study evaluated the outcomes of prostate cancer patients with persistently detectable levels of prostate-specific antigen (PSA) following radical prostatectomy (RP). Some background Radical prostatectomy or RP (surgical removal of the prostate gland and some tissue around it) is a common treatment for patients with prostate...
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In a nutshell This study used a simulation model to review the benefits and harms of either treating, or simply observing, patients diagnosed with prostate cancer by prostate specific antigen screening. Some background Prostate specific antigen (PSA) is a molecule produced by cells of the prostate gland, and is normally present at very low levels...
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In a nutshell This study compared the effect of two chemotherapy drugs used in the treatment of metastatic prostate cancer. Survival rates and pain relief were compared with cabazitaxel (jevtana) or mitoxantrone (novantrone) therapy. Some background Testosterone, the main male sex hormone, facilitates in the growth of...
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