In a nutshell This study compared treatment outcomes of prostate surgery and external beam radiation therapy (EBRT) for localized prostate cancer. While mortality rates were generally very low, prostate surgery may be more suitable for men with high-risk prostate cancer. Some background Localized prostate cancer is cancer that is confined to the...
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In a nutshell This study examined the relationship between comorbidities (other medical conditions) and cancer progression during active surveillance. Researchers reported that progression is more likely among men with 2 or more comorbidities. Some background Active surveillance of prostate cancer refers to actively monitoring tumor growth...
Read MoreIn a nutshell This phase III trial aims to evaluate if metformin (Glucophage) can delay the time to progression in men with low-risk prostate cancer. The main outcome to be investigated is disease progression based on the need for treatment or biopsy results. The trial is recruiting in several locations in Canada. The details Metformin is a drug...
Read MoreIn a nutshell This review examined predictors of disease progression in low-risk prostate cancer during active surveillance. Researchers concluded that certain blood markers, biopsy results, and ethnicity could help predict which patients were more likely to experience disease progression. Some background Active surveillance of prostate...
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In a nutshell The authors compared scar satisfaction in prostate cancer patients who underwent different surgical procedures. Some background Surgical removal of prostate gland is a common treatment in prostate cancer. There can be different types of surgical techniques. Laparascopic surgery (standard surgery) involves several small...
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In a nutshell The authors determined the association between perineural invasion (cancer on the nerves inside the prostate) and disease progression in men with prostate cancer on active surveillance (watchful waiting). Some background Active surveillance is common in early stage (stage I or II) prostate cancer. It involves actively...
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In a nutshell The authors aimed to determine the effect of phosphodiesterase type 5 inhibitors on biochemical recurrence following prostate surgery. Some background Prostate surgery is a form of treatment that involves surgically removing the prostate gland which can cause erectile dysfunction in some patients. Phosphodiesterase type 5 inhibitors...
Read MoreIn a nutshell The authors aimed to determine the effects of weight in prostate cancer progression under active surveillance. Some background Active surveillance involves actively monitoring tumor growth and development in a patient without administering treatment. Prostate cancer patients undergoing active surveillance who have a high...
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In a nutshell The authors aimed to determine if a new risk classification system could help determine treatment and outcome in individuals with intermediate-risk prostate cancer. Some background External-beam radiation therapy (EBRT) is a form of treatment that involves the application of an external radiation source focused at the site of...
Read MoreIn a nutshell The authors aimed to determine the long-term effects of early prostate cancer treatment. Some background Early prostate cancer is usually treated with active surveillance, radiation therapy, androgen deprivation therapy or surgery. Active surveillance involves the monitoring of cancer progression in a patient without administering...
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In a nutshell The authors aimed to determine whether African Americans underwent more frequent reclassifications than Caucasians on active surveillance. Some background Active surveillance involves close observation of the cancer to detect any signs of cancer progression rather than immediate treatment. This is typically carried out in...
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In a nutshell The authors aimed to determine whether moderate hypofractionated radiotherapy would worsen sexual function after treatment. Some background There are many options for treatment of low-risk prostate cancer (cancer with a very small likelihood of spreading), therefore side-effects and patient preferences may drive the decision of...
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