Current disease status-Recurrent leukemia Posts on Medivizor
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Current disease status-Recurrent leukemia Posts on Medivizor

Searching for patients with different types of leukemia to test modified stem cell transplants donated by relatives

Posted by on Sep 20, 2019 in Leukemia | 0 comments

In a nutshell This trial is examining the effectiveness of modified stem cell transplants (SCT) donated by patient relatives, which have certain immune cells removed to prevent transplant rejection in patients with leukemia and lymphoma. The main outcome will be the maximum dose of SCT that can be given safely and is effective. This study is recruiting...

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Evaluating the safety and effectiveness of the Shingrix vaccine for patients with leukemia or lymphoma

Posted by on Aug 23, 2019 in Leukemia | 0 comments

In a nutshell This study evaluated the safety and effectiveness of the herpes zoster vaccine (Shingrix) in patients with blood cancer who are receiving anti-cancer therapy. This study concluded that the Shingrix vaccine was effective in these patients, with manageable side effects. Some background Shingles is caused by a virus called herpes zoster....

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The effects of stem cell transplant on multiple relapses in acute myeloid leukemia.

Posted by on Jul 18, 2019 in Leukemia | 0 comments

In a nutshell This study analyzed the outcomes of allogeneic stem cell transplantation (alloSCT) in patients with acute myeloid leukemia (AML) who had experienced multiple relapses. The main finding was that those who received alloSCT while in complete remission for at least the third time had the best survival.   Some background Complete...

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Dasatinib second and third-line treatment in chronic phase chronic myeloid leukemia

Posted by on Jul 9, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the effectiveness and safety of dasatinib as a second- and third-line therapy in patients with chronic phase chronic myeloid leukemia (CP-CML).  This study concluded that dasatinib was effective as a second-line treatment in these patients but showed limited effectiveness as a third-line treatment....

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Blinatumomab vs chemotherapy in the treatment of relapsed or unresponsive acute lymphoblastic leukemia

Posted by on Jun 23, 2019 in Leukemia | 0 comments

In a nutshell This study compared the safety and effectiveness of blinatumomab (Blincyto) with chemotherapy in the treatment of acute lymphoblastic leukemia (ALL). Researchers found the survival was higher with blinatumomab than chemotherapy alone. Some background Patients with unresponsive or relapsed ALL treated with chemotherapy have...

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Looking for patients with Ph+ or BCR-ABL+ acute lymphoblastic leukemia to test a treatment combination

Posted by on Jun 14, 2019 in Leukemia | 0 comments

In a nutshell This phase 2 trial is evaluating the effectiveness of ponatinib (Iclusig) plus chemotherapy for patients with acute lymphoblastic leukemia (ALL) that is positive for the Philadelphia chromosome (Ph+) or the BCR-ABL gene (BCR-ABL+). The main outcome to be measured will be the number of patients who respond to treatment. This study is...

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Outcomes of stem cell transplant for patients with acute lymphoblastic leukemia after inotuzumab ozogamicin treatment

Posted by on Jun 5, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the outcomes of allogeneic stem cell transplant (allo-SCT) after treatment with inotuzumab ozogamicin (Besponsa) for patients with relapsed/unresponsive acute lymphoblastic leukemia (ALL). This study concluded that allo-SCT provided optimal long-term survival benefit for these patients. Some...

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Looking for young patients with B-cell acute lymphoblastic leukemia to test a new T-cell therapy

Posted by on Apr 22, 2019 in Leukemia | 0 comments

In a nutshell This phase 2 trial is evaluating the effectiveness of huCART19 cell therapy in young patients with high-risk B-cell acute lymphoblastic leukemia (ALL). The main outcome to be measured will be survival without a treatment-related complication. This study is being conducted in Philadelphia, Pennsylvania, United States. The details Acute...

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Searching for patients to try a new therapy for non-responsive leukemia/lymphoma after stem-cell transplant.

Posted by on Mar 15, 2019 in Leukemia | 0 comments

In a nutshell This study will investigate the effects of ibrutinib (Imbruvica) in patients with non-responsive leukemia/lymphoma after a stem-cell transplant. The main outcome that will be measured is the time after treatment before patients experience cancer worsening. This trial is recruiting in the United States. The details Some patients with...

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Is entospletinib an effective treatment for relapsed or unresponsive chronic lymphocytic leukemia?

Posted by on Mar 12, 2019 in Leukemia | 0 comments

In a nutshell This study examined if entospletinib can be used as a treatment for relapsed or unresponsive chronic lymphocytic leukemia (CLL). This study concluded entospletinib has disease reducing activity in patients with CLL, where previous treatment has failed. Some background Chronic lymphocytic leukemia (CLL) is a cancer of the bone marrow. It...

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Effectiveness of venetoclax in patients with unresponsive chronic lymphocytic leukemia

Posted by on Mar 9, 2019 in Leukemia | 0 comments

In a nutshell This study looked at the effectiveness of venetoclax (Venclexta) in the treatment of relapsed or unresponsive chronic lymphocytic leukemia (CLL). Researchers found venetoclax improved outcomes in these patients. Some background CLL is a cancer of the bone marrow. This may lead to an abnormal immune system. It is also often...

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