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Current disease status-First occurrence of the leukemia Posts on Medivizor

The effects of single and multi-agent chemotherapies in older patients with newly diagnosed acute myeloid leukemia

Posted by on Mar 16, 2020 in Leukemia | 0 comments

In a nutshell The study compared the effects of single and multi-agent chemotherapies on survival in older patients with newly diagnosed acute myeloid leukemia (AML) in a real-world setting. The main finding was that chemotherapy with multiple drugs improved survival in such patients, compared to single-agent therapy. Some background Older patients...

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The comparison of outcomes of two salvage therapies in patients with relapsed or unresponsive acute myeloid leukemia

Posted by on Mar 4, 2020 in Leukemia | 0 comments

In a nutshell The study evaluated the effectiveness of two salvage therapies – mitoxantrone (Novantrone), etoposide (Etopophos), and cytarabine (Cytosar-U) also known as MEC and cladribine (Leustatin), cytarabine, filgrastim (Neupogen), and mitoxantrone also known as CLAG-M, for treating relapsed/refractory acute myeloid leukemia...

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The effects of treatment switching from imatinib to nilotinib in patients with chronic phase-chronic myeloid leukemia

Posted by on Feb 29, 2020 in Leukemia | 0 comments

In a nutshell The study investigated the effects of switching treatment to nilotinib (Tasigna) after initial therapy with imatinib (Gleevec) in patients with chronic phase of chronic myeloid leukemia (CP-CML). The authors found that switching to nilotinib after imatinib initial treatment is convenient and effective in such patients. Some background...

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How useful is preimplantation genetic testing for aneuploidy for fertility preservation in cancer patients?

Posted by on Feb 22, 2020 in Leukemia | 0 comments

In a nutshell This study investigated preimplantation genetic testing for aneuploidy (PGT-A) for fertility preservation (FP).  They found that PGT-A was useful in cancer patients attempting FP.  Some background Assisted reproductive technology (ART) is used to treat infertility. It is also an important option for cancer patients. Cancer...

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Evaluating outcomes after higher doses of PEG-asparaginase and intense intrathecal therapy in children with high-risk acute lymphoblastic leukemia

Posted by on Jan 20, 2020 in Leukemia | 0 comments

In a nutshell This study investigated if a higher dose of PEG-asparaginase (Oncaspar) with early induction and additional triple intrathecal therapy (TIT) can prevent relapse in the brain in children with acute lymphoblastic leukemia (ALL). The authors found that additional TIT during early induction improved the outcomes of these...

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Comparing new-generation tyrosine kinase inhibitors and imatinib in patients with newly diagnosed chronic myeloid leukemia

Posted by on Dec 24, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to compare the effectiveness of new-generation tyrosine kinase inhibitors and imatinib in patients with newly diagnosed chronic myeloid leukemia.  This study concluded that for first-line treatment, new-generation tyrosine kinase inhibitors are better than imatinib.  Some background Tyrosine...

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Evaluating the safety and effectiveness of the Shingrix vaccine for patients with leukemia or lymphoma

Posted by on Aug 23, 2019 in Leukemia | 0 comments

In a nutshell This study evaluated the safety and effectiveness of the herpes zoster vaccine (Shingrix) in patients with blood cancer who are receiving anti-cancer therapy. This study concluded that the Shingrix vaccine was effective in these patients, with manageable side effects. Some background Shingles is caused by a virus called herpes zoster....

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Immunoglobulin levels at diagnosis and outcomes of patients with chronic lymphocytic leukemia

Posted by on Aug 13, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the relationship between immunoglobulin (Ig) levels and clinical outcomes in patients with chronic lymphocytic leukemia.  This study concluded that levels of IgG and IgA at diagnosis are important prognostic markers for infection in these patients.  Some background Immunoglobulins (Ig)...

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