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Current disease status-First occurrence of the leukemia Posts on Medivizor

Looking for older patients with acute myeloid leukemia to test a new treatment combination

Posted by on Jun 14, 2019 in Leukemia | 0 comments

In a nutshell This study is evaluating how well CPI-613 plus chemotherapy works in older patients with acute myeloid leukemia (AML) that has come back or stopped responding to treatment. The main outcome to be measured will be the number of patients who have a complete disappearance of all signs of cancer. This trial is taking place across the United...

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Comparing complete remission in patients with acute myeloid leukemia who receive standard or high-dose chemotherapy

Posted by on Apr 24, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to compare levels of early complete remission in patients with acute myeloid leukemia (AML) treated with standard or sequential high-dose chemotherapy.  This study concluded that sequential high-dose chemotherapy led to early complete remission in these patients.  Some background Sequential high-dose...

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Looking for young patients with B-cell acute lymphoblastic leukemia to test a new T-cell therapy

Posted by on Apr 22, 2019 in Leukemia | 0 comments

In a nutshell This phase 2 trial is evaluating the effectiveness of huCART19 cell therapy in young patients with high-risk B-cell acute lymphoblastic leukemia (ALL). The main outcome to be measured will be survival without a treatment-related complication. This study is being conducted in Philadelphia, Pennsylvania, United States. The details Acute...

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Looking for elderly patients with chronic lymphocytic leukemia to test a treatment combination

Posted by on Mar 16, 2019 in Leukemia | 0 comments

In a nutshell This trial is examining the effectiveness of ibrutinib and obinutuzumab with or without venetoclax in the treatment of older patients with chronic lymphocytic leukemia (CLL). The main outcome to be measured will be survival without cancer worsening. This trial is recruiting in the United States. The details Patients with CLL are often...

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Long-term effectiveness of tyrosine kinase inhibitors for newly diagnosed chronic-phase chronic myeloid leukemia

Posted by on Mar 16, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the long-term safety and effectiveness of tyrosine kinase inhibitors for chronic-phase chronic myeloid leukemia. This study concluded that the outcomes for these patients are satisfactory and reliable. Some background Patients with chronic phase chronic myeloid leukemia (CP-CML) generally have mild...

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Searching for patients with newly-diagnosed AML to try this new treatment option

Posted by on Mar 15, 2019 in Leukemia | 0 comments

In a nutshell This Phase 3 study is evaluating the safety and effectiveness of midostaurin (Rydapt) combined with chemotherapy for patients with newly-diagnosed acute myeloid leukemia (AML). The main outcome to be measured will be event-free survival at 5 years. The details Previous studies have shown that midostaurin combined with chemotherapy is...

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Combining ibrutinib and umbralisib to treat relapsed/unresponsive chronic lymphocytic leukemia

Posted by on Feb 28, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the safety and effectiveness of ibrutinib (Imbruvica) combined with umbralisib for patients with released/unresponsive chronic lymphocytic leukemia (CLL). This study concluded that the combination of umbralisib and ibrutinib is well tolerated and effective in relapsed/unresponsive CLL.  Some background...

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Treatment of childhood ALL with therapy to the spinal area

Posted by on Feb 28, 2019 in Leukemia | 0 comments

In a nutshell This study looked at the use of medication delivered to the spinal area (intrathecal) in patients with acute lymphoblastic leukemia (ALL). Researchers showed that this may be used instead of radiation to the head in these patients, with similar outcomes. Some background Acute lymphoblastic leukemia is a cancer of the immune system that...

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Evaluating nilotinib with chemotherapy for acute lymphoblastic leukemia with abnormal genes

Posted by on Jan 31, 2019 in Leukemia | 0 comments

In a nutshell This study wanted to assess the safety and effectiveness of nilotinib (Tasigna) in the treatment of acute lymphoblastic leukemia (ALL) with abnormal genes. Researchers found that nilotinib was safe and effective in these patients when combined with chemotherapy. Some background Acute lymphoblastic leukemia (ALL) is a cancer of the immune...

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