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Current disease status-First occurrence of the leukemia Posts on Medivizor

Evaluating different frontline treatment combinations for chronic lymphocytic leukemia

Evaluating different frontline treatment combinations for chronic lymphocytic leukemia

Posted by on Jun 13, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the safety and effectiveness of different chemotherapy and targeted therapy combinations given as frontline treatment in patients with chronic lymphocytic leukemia in a real-world setting.  This study concluded that some treatments have a real-world activity that is comparable to clinical trial...

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Maintenance treatment impact on sleep-wake rhythms and cancer-related fatigue in children with acute lymphoblastic leukemia

Maintenance treatment impact on sleep-wake rhythms and cancer-related fatigue in children with acute lymphoblastic leukemia

Posted by on May 16, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the impact of maintenance treatment on cancer-related fatigue and sleep-wake rhythms in pediatric patients with acute lymphoblastic leukemia.   This study concluded that sleep-wake rhythms are disturbed, physical activity levels lower and cancer-related fatigue levels higher...

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Long-term effects of ofatumumab and chlorambucil in previously untreated patients with chronic lymphocytic leukemia

Posted by on Apr 25, 2020 in Leukemia | 0 comments

In a nutshell The study evaluated the long-term effectiveness and safety of Ofatumumab (Arzerra) and chlorambucil (Leukeran) (CHL) in patients with previously untreated chronic lymphocytic leukemia (CLL). The authors found that the combination therapy safely improved clinical outcomes in such patients in 5 years, compared to chlorambucil alone. Some...

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Evaluating imatinib treatment in children and adolescents with chronic myeloid leukemia

Posted by on Apr 19, 2020 in Leukemia | 0 comments

In a nutshell The study evaluated the effectiveness and safety of imatinib (Gleevec) in treating children and adolescents with chronic myeloid leukemia (CML). The main finding was that imatinib was effective against CML and safe in this patient population. Some background Imatinib deactivates a cancerous enzyme called BCR-ABL1. Lately, imatinib...

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The effects of single and multi-agent chemotherapies in older patients with newly diagnosed acute myeloid leukemia

Posted by on Mar 16, 2020 in Leukemia | 0 comments

In a nutshell The study compared the effects of single and multi-agent chemotherapies on survival in older patients with newly diagnosed acute myeloid leukemia (AML) in a real-world setting. The main finding was that chemotherapy with multiple drugs improved survival in such patients, compared to single-agent therapy. Some background Older patients...

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The comparison of outcomes of two salvage therapies in patients with relapsed or unresponsive acute myeloid leukemia

Posted by on Mar 4, 2020 in Leukemia | 0 comments

In a nutshell The study evaluated the effectiveness of two salvage therapies – mitoxantrone (Novantrone), etoposide (Etopophos), and cytarabine (Cytosar-U) also known as MEC and cladribine (Leustatin), cytarabine, filgrastim (Neupogen), and mitoxantrone also known as CLAG-M, for treating relapsed/refractory acute myeloid leukemia...

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The effects of treatment switching from imatinib to nilotinib in patients with chronic phase-chronic myeloid leukemia

Posted by on Feb 29, 2020 in Leukemia | 0 comments

In a nutshell The study investigated the effects of switching treatment to nilotinib (Tasigna) after initial therapy with imatinib (Gleevec) in patients with chronic phase of chronic myeloid leukemia (CP-CML). The authors found that switching to nilotinib after imatinib initial treatment is convenient and effective in such patients. Some background...

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How useful is preimplantation genetic testing for aneuploidy for fertility preservation in cancer patients?

Posted by on Feb 22, 2020 in Leukemia | 0 comments

In a nutshell This study investigated preimplantation genetic testing for aneuploidy (PGT-A) for fertility preservation (FP).  They found that PGT-A was useful in cancer patients attempting FP.  Some background Assisted reproductive technology (ART) is used to treat infertility. It is also an important option for cancer patients. Cancer...

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