Current disease phase-Chronic phase Page 2 Posts on Medivizor
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Current disease phase-Chronic phase Posts on Medivizor

Chromosomal abnormalities at diagnosis does not predict long-term treatment outcomes with tyrosine kinase inhibitors

Posted by on Jan 28, 2018 in Leukemia | 0 comments

In a nutshell This study examined whether chromosomal abnormalities at diagnosis can predict treatment outcomes with TKIs in chronic myeloid leukemia (CML). Researchers reported similar long-term treatment outcomes in patients with and without chromosomal abnormalities at diagnosis. Some background CML is a disease in which the bone marrow makes...

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An analysis comparing reduced-intensity conditioning and myeloablative therapy for CLL

Posted by on Dec 30, 2017 in Leukemia | 0 comments

In a nutshell This study analyzed the results of 37 studies comparing myeloablative therapy and reduced intensity conditioning (RIC) before stem cell transplantation in patients with chronic lymphocytic leukemia (CLL). This study concluded that RIC was associated with lower mortality and better survival compared to myeloablative therapy. Some...

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Modern treatment approaches for chronic-phase CML

Posted by on Oct 25, 2017 in Leukemia | 0 comments

In a nutshell This study reviewed evidence of novel agents in the treatment of chronic myeloid leukemia (CML). Some background CML is a disease in which the bone marrow makes too many mature and immature white blood cells. It is typically a slowly progressing disease that occurs mainly during or after middle age. Most patients are diagnosed in the...

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The impact of imatinib on male fertility

Posted by on Sep 26, 2017 in Leukemia | 0 comments

In a nutshell This study examined whether imatinib (Gleevac) affects the fertility of men with chronic myeloid leukemia (CML). Researchers concluded that imatinib reduced sperm density, sperm count, sperm survival and activity when compared to healthy control participants.  Some background CML has three phases: chronic, accelerated, and...

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Is stem cell transplantation a viable option among AML patients who are not in remission?

Posted by on Sep 3, 2017 in Leukemia | 0 comments

In a nutshell This study examined stem cell transplant outcomes across acute myeloid leukemia (AML) patients with different disease status. Researchers reported superior survival after a stem cell transplant among patients in second complete remission.  Some background Stem cell transplantation is considered the most effective therapy for...

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Examining complete molecular response to treatment with different doses of imatinib

Posted by on Apr 7, 2017 in Leukemia | 0 comments

In a nutshell This study examined the extent and effect of complete treatment response (on a molecular level) in patients treated with imatinib (Gleevac) for chronic myeloid leukemia (CML). Researchers reported that a high proportion of patients treated with imatinib reached complete molecular remission, particularly when given at a high dose. Complete...

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Peripheral arterial occlusive disease in chronic myeloid leukemia treated with TKI therapy

Posted by on Apr 7, 2017 in Leukemia | 0 comments

In a nutshell This study compared the rates of peripheral arterial occlusive disease (PAOD) in chronic myeloid leukemia (CML) patients treated with different therapies. The authors concluded that nilotinib (Tasigna) was associated with higher rates of PAOD than other treatments. Some background Tyrosine kinase inhibitors (TKIs) are now the...

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