Current disease phase-Chronic phase Posts on Medivizor
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Current disease phase-Chronic phase Posts on Medivizor

Evaluating allogeneic hematopoietic cell transplantation in patients with chronic myeloid leukemia who are resistant or intolerant to tyrosine kinase inhibitors

Evaluating allogeneic hematopoietic cell transplantation in patients with chronic myeloid leukemia who are resistant or intolerant to tyrosine kinase inhibitors

Posted by on May 30, 2021 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the effectiveness of allogeneic hematopoietic stem cell transplantation (alloHSCT) in patients with chronic-phase chronic myeloid leukemia (CP-CML) who are resistant or intolerant to tyrosine kinase inhibitor (TKI) treatment.  This study concluded that...

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Comparing nilotinib and dasatinib as second line treatment in patients with chronic myeloid leukemia in a real-life setting

Comparing nilotinib and dasatinib as second line treatment in patients with chronic myeloid leukemia in a real-life setting

Posted by on Apr 11, 2021 in Leukemia | 0 comments

In a nutshell This study aimed to compare dasatinib (Sprycel) and nilotinib (Tasigna) as second-line treatments for patients with chronic-phase (CP) chronic myeloid leukemia (CML) in a real-life setting.   This study concluded that both dasatinib and nilotinib are equally effective and well...

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Can molecular response to imatinib indicate treatment response in patients with chronic myeloid leukemia?

Posted by on Feb 20, 2020 in Leukemia | 0 comments

In a nutshell The study evaluated if the molecular response to Imatinib (Gleevec) is a proper way to judge treatment progress in Iranian patients with chronic-phase chronic myeloid leukemia (CP-CML). The main finding was that survival was improved in patients who had a better molecular response to imatinib. Some background Patients with...

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Which factors affect the safety and effectiveness of imatinib treatment for newly diagnosed chronic myeloid leukemia?

Posted by on Jan 7, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the safety and effectiveness of imatinib treatment in patients with newly diagnosed chronic myeloid leukemia. This study concluded that patients of lower weight and older age are more vulnerable to side effects.  Some background Imatinib (Gleevec) is a targeted therapy...

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Are the currently prescribed doses of tyrosine kinase inhibitors too high for elderly patients with chronic myeloid leukemia?

Posted by on Dec 15, 2019 in Leukemia | 0 comments

In a nutshell This study investigated the prescribed doses of tyrosine kinase inhibitors (TKIs) and the outcomes of elderly patients with chronic myeloid leukemia (CML). The study concluded that the currently prescribed TKI dose might be higher than necessary in elderly patients. Some background TKIs such as imatinib (Glivec), dasatinib...

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Outcomes od BCR-ABL mutated chronic myeloid leukemia patients who have failed tyrosine kinase inhibitors

Posted by on Aug 16, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the frequency of BCR-ABL kinase domain mutation detection and its prognostic significance in patients with chronic-phase chronic myeloid leukemia (CP-CML) treated with tyrosine kinase inhibitors (TKIs).  This study concluded that early mutation detection and use of 2nd and...

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