In a nutshell This study investigated the interactions between tyrosine kinase inhibitors and other drugs taken at the same time in patients with chronic myeloid leukemia. This study concluded that drug interactions were found in a significant number of patients, with mild side effects. Some background Imatinib (Gleevec) and similar drugs are the...
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Bendamustine and rituximab as salvage treatment in chronic lymphocytic leukemia
In a nutshell This study aimed to measure the effectiveness of bendamustine and rituximab as salvage treatment in patients with chronic lymphocytic leukemia. This study concluded that bendamustine and rituximab are as effective as ibrutinib as salvage treatment in these patients. Some background The standard treatment for chronic lymphocytic...
Read MoreComparing treatment options for CML and ALL patients with the T315I mutation
In a nutshell This paper compared ponatinib (Iclusib) and stem cell transplantation in leukemia patients with an abnormality on the T315I gene. Patients with acute lymphoblastic leukaemia (ALL) positive for the Philadelphia chromosome and patients with chronic myeloid leukaemia (CML) were studied. Authors reported improved survival with...
Read MoreStem cell transplantation in chronic myeloid leukemia
In a nutshell This review discussed the role of stem cell transplantation in patients with chronic myeloid leukemia. Some background Stem cell (immature blood cell) transplantation (SCT) has had a long history in the treatment of chronic myeloid leukemia (CML). Patients who have a matched donor (someone who is a close genetic match, such as a...
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