Confined or spread disease-Spread into the peritoneum - Page 3 of 4 Posts on Medivizor
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Confined or spread disease-Spread into the peritoneum Posts on Medivizor

Evaluating the safety and efficacy of adding bevacizumab in two capecitabine-based chemotherapy regimens for the treatment of patients with metastatic colorectal cancer

Evaluating the safety and efficacy of adding bevacizumab in two capecitabine-based chemotherapy regimens for the treatment of patients with metastatic colorectal cancer

Posted by on Jul 23, 2013 in Colorectal cancer | 0 comments

In a nutshell This phase II clinical trial investigated the addition of bevacizumab to two chemotherapy regimens for the first line treatment of patients with metastatic colorectal cancer (CRC). Some background Cancer cells need blood supply in order to grow. They do so by forming new blood vessels, thus feeding themselves. Bevacizumab (Avastin)...

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Intermittent versus continuous chemotherapy in advanced colorectal cancer

Posted by on Jun 11, 2013 in Colorectal cancer | 0 comments

In a nutshell The aim of this study was to assess the effects of pauses during chemotherapy in patients with advanced colorectal cancer (CRC).  Some background In advanced CRC (cancer of the large bowel that has spread to the lymph nodes and other tissues and organs of the body) the cancer is more difficult to remove. Patients usually need...

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Evaluating the benefits of laparoscopy in determining the extent of peritoneal carcinomatosis for patients with colorectal cancer

Evaluating the benefits of laparoscopy in determining the extent of peritoneal carcinomatosis for patients with colorectal cancer

Posted by on May 13, 2013 in Colorectal cancer | 0 comments

In a nutshell This article evaluated whether the use of a minimally invasive diagnostic technique called laparoscopy before surgery to treat peritoneal carcinomatosis improves the selection of patients who can benefit the most from treatment. The authors of the study found that laparoscopy can be used to select patients for whom surgery may be a...

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Early post-operative intraperitoneal chemotherapy (EPIC) and hyperthermic intraperitoneal chemotherapy (HIPEC) after cytoreductive surgery (CRS) for cancers of the appendix, colon or rectum

Posted by on Apr 19, 2013 in Colorectal cancer | 0 comments

In a nutshell This study will compare two procedures to deliver chemotherapy into the abdominal cavity following surgery to remove colorectal cancer spread to the peritoneum (the lining of the abdominal cavity).  The primary outcome of the study is disease-free survival, or the length of time without any evidence of cancer. The details...

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Defining patients with a high risk of developing peritoneal carcinomatosis after curative surgery

Defining patients with a high risk of developing peritoneal carcinomatosis after curative surgery

Posted by on Apr 13, 2013 in Colorectal cancer | 0 comments

In a nutshell The objective of this study was to identify risk factors predictive for developing peritoneal carcinomatosis (PC) after curative surgery for colorectal cancer (CRC). The data show three situations that could result in a real risk of recurrent PC: synchronous PC, synchronous isolated ovarian metastases and a perforated primary tumor. There...

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Phase II clinical trial evaluating the combination of cetuximab and erlotinib for the treatment of patients with metastatic colorectal cancer

Phase II clinical trial evaluating the combination of cetuximab and erlotinib for the treatment of patients with metastatic colorectal cancer

Posted by on Mar 19, 2013 in Colorectal cancer | 0 comments

In a nutshell This article presents the results of a phase II clinical trial that evaluated the efficacy and safety of the combination of two targeted therapies – cetuximab and erlotinib – for patients with metastatic colorectal cancer (mCRC). Some background Colorectal cancer that has spread outside the large...

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XELIRI-bevacizumab versus FOLFIRI-bevacizumab as primary treatment for patients with metastatic colorectal cancer

XELIRI-bevacizumab versus FOLFIRI-bevacizumab as primary treatment for patients with metastatic colorectal cancer

Posted by on Mar 13, 2013 in Colorectal cancer | 0 comments

In a nutshell The present clinical trial compared two chemotherapy regimens as first-line treatment for patients with metastatic colorectal cancer (mCRC): XELIRI-bevacizumav versus FOLFIRI-bevacizumab. Some background Approximately one quarter of patients with colorectal cancer (cancer in the large intestine) have metastases,...

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Operative versus non-operative treatment for recurrent rectal cancer: impact on long-term survival

Operative versus non-operative treatment for recurrent rectal cancer: impact on long-term survival

Posted by on Mar 12, 2013 in Colorectal cancer | 0 comments

In a nutshell The present paper compares long-term survival rates of surgery versus non-operative treatments in patients with recurrent rectal cancer (RRC). Some background Rectal cancer is cancer in the final section of the large intestine, or rectum. Surgery to remove the cancer is the first choice of treatment, but chemotherapy with or...

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Phase I trial to determine the safety of a new anti-cancer drug: PD 0332991

Phase I trial to determine the safety of a new anti-cancer drug: PD 0332991

Posted by on Mar 7, 2013 in Colorectal cancer | 0 comments

In a nutshell This article presents the results from the first human trial of PD 0332991, a new anti-cancer drug. The main objective of the study was to determine the safety and recommended dose for further testing. Results warrant further studies and revealed that neutropenia (low white cell count) was the main side effect. Some background Cells...

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Comparison of two surgical techniques for the treatment of pseudomyxoma peritonei

Comparison of two surgical techniques for the treatment of pseudomyxoma peritonei

Posted by on Mar 4, 2013 in Colorectal cancer | 1 comment

In a nutshell The present study compared the efficacy of two surgical techniques to treat pseudomyxoma peritonei (PMP): debulking and cytoreduction. Cytoreductive surgery achieved better surgical results and yielded higher 3- and 5-year survival rates, compared with debulking. Some background PMP is a rare condition caused by the production of...

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