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Confined or spread disease-Spread into regional lymph nodes Posts on Medivizor

Clarithromycin administered daily reduces the skin-related side effects associated with panitumumab treatment for metastatic colorectal cancer.

Clarithromycin administered daily reduces the skin-related side effects associated with panitumumab treatment for metastatic colorectal cancer.

Posted by on Sep 5, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of preventative antibiotic treatment with clarithromycin (Biaxin) to prevent skin-related side effects associated with panitumumab (Vectibix) treatment for patients with metastatic colorectal cancer (mCRC). The data showed that clarithromycin administered daily along with a simple...

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Evaluating the effectiveness and safety of chemotherapy before surgery for locally advanced colon cancer.

Evaluating the effectiveness and safety of chemotherapy before surgery for locally advanced colon cancer.

Posted by on Jul 11, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the safety, effectiveness, and side effect profile of chemotherapy given before surgery for the treatment of patients with locally advanced colon cancer (LACC). The data showed that this treatment was safe and effective with manageable side effects for these patients. Some background Colorectal cancer (CRC) is one...

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Evaluating surgery and chemotherapy versus chemotherapy alone for the treatment of metastatic colorectal cancer.

Evaluating surgery and chemotherapy versus chemotherapy alone for the treatment of metastatic colorectal cancer.

Posted by on Mar 31, 2021 in Colorectal cancer | 0 comments

In a nutshell This study evaluated whether surgery of colorectal cancer (CRC) followed by chemotherapy (CT) improved the outcomes of patients with metastatic (spread) CRC compared to CT alone. The study found that there was no difference in patients' outcomes whether surgery was given or not. Some background CRC is the third most common cancer...

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CT-guided radioactive implant improves the outcomes of locally advanced rectal cancer

CT-guided radioactive implant improves the outcomes of locally advanced rectal cancer

Posted by on Mar 28, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of computed tomography (CT)-guided radioactive 125Iodine (RI) implantation in patients with recurrent locally advanced rectal cancer (LARC). Researchers suggested that CT-guided RI implantation is a good and safe treatment for patients with LARC that came back...

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How long should patients with locally advanced rectal cancer wait between chemoradiotherapy and surgery to achieve the best outcome?

How long should patients with locally advanced rectal cancer wait between chemoradiotherapy and surgery to achieve the best outcome?

Posted by on Feb 26, 2021 in Colorectal cancer | 0 comments

In a nutshell This study evaluated the timing between chemoradiotherapy (CRT) and surgery in patients with locally advanced rectal cancer (LARC). The study found that patients who had surgery more than 10 weeks after CRT had the best outcome. Some background Rectal cancer is commonly treated with surgery to remove the tumor. LARC is...

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Evaluating the use of radiotherapy followed by chemotherapy before surgery for locally-advanced rectal cancer.

Evaluating the use of radiotherapy followed by chemotherapy before surgery for locally-advanced rectal cancer.

Posted by on Feb 14, 2021 in Colorectal cancer | 0 comments

In a nutshell This trial looked at the use of short-course radiotherapy (RT) followed by chemotherapy (CT) and delayed surgery to reduce distant metastases (tumor spread) in patients with locally advanced rectal cancer (LARC). The trial found that this treatment was more effective in controlling distant metastases when compared to standard...

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Pembrolizumab as a treatment for advanced colorectal cancer predisposed to mutations.

Pembrolizumab as a treatment for advanced colorectal cancer predisposed to mutations.

Posted by on Jan 10, 2021 in Colorectal cancer | 0 comments

In a nutshell This study compared the use of pembrolizumab (Keytruda) to chemotherapy for the treatment of patients with colorectal cancer (CRC) and high microsatellite instability (MI). This study showed that patients who received pembrolizumab had a better outcome than those who were given chemotherapy. Some background Patients who are...

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Is completion of irinotecan chemotherapy associated with better treatment response in locally advanced rectal cancer?

Is completion of irinotecan chemotherapy associated with better treatment response in locally advanced rectal cancer?

Posted by on Jul 5, 2020 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness of high completion of irinotecan (Camptosar) chemotherapy before locally advanced rectal cancer surgery. Researchers suggested that the completion of irinotecan chemotherapy was associated with better tumor response in these patients. Some background Colorectal cancer is the third most...

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A longer interval between chemoradiotherapy and surgery improves rectal cancer outcomes

Posted by on Dec 23, 2019 in Colorectal cancer | 0 comments

In a nutshell This study compared the effects of different time intervals between chemotherapy and radiation therapy (CRT) and rectal cancer surgery. Researchers suggested that increasing this interval from 8 weeks to 12 weeks improved treatment response. Some background Over 70% of patients with rectal cancer have locally advanced disease at...

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Vitamin D is associated with improved survival outcomes of patients with advanced colorectal cancer

Posted by on Nov 29, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the association between vitamin D blood levels and survival outcomes in patients with metastatic colorectal cancer (mCRC). Researchers suggested that higher levels of vitamin D in the blood were associated with better survival. Some background CRC is the third most common cancer in the US. Among CRC patients, only...

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Waiting at least 8 weeks for surgery after chemoradiotherapy increases rectal cancer response

Posted by on Jul 28, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the best interval time between chemoradiation therapy and rectal cancer surgery for the best outcomes in patients with rectal cancer. Researchers suggested that waiting at least 8 weeks until the surgery increases the tumor response to the treatment. Some background The standard treatment for locally advanced...

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Does lymph node yield predict survival in locally advanced rectal cancers?

Posted by on Jul 21, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the impact of lymph node yield (LNY) on the outcomes of patients with locally advanced rectal cancer. Researchers suggested that a LNY of 12 or more predict improved survival in these patients. Some background Colorectal cancer is the third most common cancer worldwide. Some patients present with locally advanced...

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