In a nutshell The study aimed to identify cardiovascular (heart and blood vessel) adverse drug reactions (CV-ADR) associated with ibrutinib treatment. This study concluded that severe and sometimes fatal cardiac events occur in patients exposed to ibrutinib. Some background Ibrutinib (Imbruvica) is a...
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In a nutshell This study aimed to compare the side effects associated of ibrutinib treatment for elderly patients with chronic lymphoid leukemia. This study concluded that ibrutinib treatment in these patients was not associated with significantly higher risks of anemia (low red blood cells), thrombocytopenia...
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In a nutshell This study investigated the effectiveness of epidermal growth factor (EGF) ointment to treat skin side effects in patients with non-small cell lung cancer (NSCLC) receiving epidermal growth factor receptor (EGFR) inhibitor treatment. Researchers suggested that EGF ointment improves the outcomes and quality of life of these patients. Some...
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In a nutshell This study investigated the effectiveness of epidermal growth factor (EGF) ointment to treat skin side effects in patients with colorectal cancer receiving epidermal growth factor receptor (EGFR) inhibitor treatment. Researchers suggested that EGF ointment improves the outcomes and quality of life of these patients. Some background...
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In a nutshell This study evaluated whether FDG-PET/CT scanning could help predict side effects from bleomycin (Blenoxane) in patients with Hodgkin lymphoma (HL) treated with ABVD chemotherapy (doxorubicin, bleomycin, vinblastine, dacarbazine). This study concluded that this type of scanning could help predict lung side effects earlier than other clinical...
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In a nutshell This study aimed to investigate the impact of early side effects requiring ado-trastuzumab emtansine dose interruptions or reductions on outcomes for patients with HER2+ advanced metastatic breast cancer. This study concluded that these side effects do not impact the outcomes for these patients. Some background...
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In a nutshell This study examined if a modified version of doxorubicin (Adriamycin) in ABVD chemotherapy was safe and effective in patients with Hodgkin’s lymphoma who had heart disease. This study found that this regimen was safer and just as effective as conventional ABVD. Some background Hodgkin’s lymphoma (HL) is a cancer of white...
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In a nutshell This study investigated the impact of levodopa treatment on the quality of life of patients with Parkinson's disease. Researchers suggested that levodopa is associated with negative side effects that decrease the quality of life of these patients. Some background Parkinson's disease (PD) is the second most common brain...
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In a nutshell This study investigated the effectiveness and side effects on the heart of anthracycline-based therapies (ABTs) for breast cancer. They found that non-doxorubicin (non-DXR) ABTs had a better benefit/risk ratio (BRR) than DXR alone. Some background Anthracycline-based therapies (ABTs) are commonly used to treat breast...
Read MoreIn a nutshell This study summarised the side effects of ibrutinib (Imbruvica) and how to manage them. Some background Ibrutinib is an FDA approved drug used to treat lymphoma and leukemia. It works on the immune cells in the body which may lead to many side effects. These include diarrhea, upper respiratory infections, bleeding, tiredness, and...
Read MoreIn a nutshell This study summarised the side effects of ibrutinib (Imbruvica) and how to manage them. Some background Ibrutinib is an FDA approved drug used to treat lymphoma and leukemia. It works on the immune cells in the body which may lead to many side effects. These include diarrhea, upper respiratory infections, bleeding, tiredness,...
Read MoreIn a nutshell This article reviewed the most common side effects of regorafenib (Stivarga) treatment for patients with metastatic (spread) colorectal cancer (mCRC). The author suggested methods to prevent these side effects to increase treatment adherence. Some background The standard treatment for mCRC is chemotherapy combined with...
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