In a nutshell This study aimed to determine the effectiveness of a closed-loop delivery system in type 1 diabetes patients living at home. Some background An insulin pump allows the patient to enter the carbohydrate content of a meal, releasing an appropriate amount of insulin based on this estimation. A continuous glucose monitor is a...
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In a nutshell This trial investigated whether an artificial pancreas could automatically adjust the insulin dose when an initial insulin dose was administered based on an individual's weight. Some background A bihormonal bionic pancreas is an artificial pancreas. This system consists of a continuous glucose monitor (CGM) and an...
Read MoreIn a nutshell This study examined the use of smartphone technology to automate the glucose monitoring and insulin delivery systems of an artificial pancreas. Some background The artificial pancreas, which delivers insulin through an insulin pump implanted in the abdomen based on continuous monitoring of blood glucose (sugar) levels, is an...
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In a nutshell This study compared blood glucose control between a bionic pancreas and insulin pump in patients with type 1 diabetes. Some background Type 1 diabetes is a chronic, progressive disease occurring due to lack of insulin production in the body. There are several treatments available to help reduce blood sugar in order to prevent or...
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In a nutshell This review assessed the development and use of an artificial pancreas (a bi-hormonal closed loop system) in the management of type 1 diabetes mellitus. Some background A normally functioning pancreas releases both insulin and the hormone glucagon. Glucagon acts in opposition to insulin, raising blood glucose levels when they become...
Read MoreIn a nutshell This trial will evaluate the safety and effectiveness of the Hybrid Closed Loop (HCL) system in adult and pediatric patients with type 1 diabetes. The primary outcome of this study will be a change in HbA1c levels (average blood glucose over 3 months). The details HCL systems are a diabetes management strategy. They are composed of...
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In a nutshell This study looked at using a closed-loop system, which connects glucose tests automatically to an insulin pump, for children with type 1 diabetes (T1D). It found that a closed-loop system improved glucose control in these patients. Some background T1D is a condition in which the pancreas is unable to create the hormone insulin,...
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