In a nutshell This study examined the benefit of radiation to limited sites of cancer spread (metastases) in men no longer responding to hormone therapy. Researchers reported effective local cancer control after radiation of lymph node metastases in patients no longer responding to hormone therapy. Some background Hormone therapy is the...
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In a nutshell This study examined the effect of androgen deprivation therapy (ADT) on the risk of cardiovascular events (such as stroke or heart attack) in men treated with radiation therapy. Researchers concluded that ADT use during or after radiation therapy increases the risk of cardiovascular events. Some background Radiation therapy is a...
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In a nutshell This study examined predictors of mortality risk in older prostate cancer patients treated with surgery. Authors reported that blood vessel disorders, severity of a whole-body disease, smoking status, and education level were significant predictors of mortality in older men treated with surgery. Some background Radical treatment...
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In a nutshell This study examined evidence for the role of prostate surgery in treating high-risk prostate cancer. Authors concluded that surgery is an effective primary treatment option for men with high-risk disease. Some background Localized prostate cancer is cancer that is confined to the prostate gland. Men with high-risk localized prostate...
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In a nutshell This study examined whether immunotherapy with sipuleucel-T (Provenge) shows a greater immune response if administered before or after androgen deprivation therapy (ADT). Authors present preliminary evidence of improved immune cell response when sipuleucel-T was administered first in patients with recurrent prostate cancer at high risk of...
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In a nutshell This study examined the benefit of biopsies guided by multiple imaging techniques (scans that provide images of the interior of the body) in men managed with active surveillance. Researchers reported improved detection rates of disease progression when biopsies were guided by multiple imaging techniques. Some background Many men with...
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In a nutshell This study examined erectile function following treatment of prostate cancer with focal therapy. Researchers reported a return of erectile function from 6 months after focal therapy. Some background Surgery and radiation are first-line treatments for localized (confined) prostate cancer. In some cases, focal therapies are recommended...
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In a nutshell This study examined the incidence of metastatic disease (cancer that spreads) progression in men undergoing active surveillance. Authors concluded that active surveillance is an appropriate management of selected patients with low- to intermediate-risk prostate cancer. Only 3.1% of men progressed over an average follow-up of 6.4...
Read MoreIn a nutshell This study examined the effect of cholesterol-lowering drugs (statins) on treatment outcomes following prostate surgery. Researchers found no link between statin use and disease recurrence risk after treatment with prostate surgery. Some background Statins are drugs that lower the cholesterol levels in the blood. Lower cholesterol...
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In a nutshell This study examined the link between smoking and the risk of mortality from prostate cancer. Authors reported that smoking increased mortality risk in patients with prostate cancer, particularly for heavier smokers. Some background Advances in early detection of prostate cancer have led to a growing number of men living with...
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In a nutshell This study examined the benefit of administering chemotherapy before prostate surgery in men with intermediate- to high-risk prostate cancer. Researchers reported preliminary evidence of a cancer-specific survival benefit when chemotherapy was administered before surgery. Some background Prostate surgery is a first-line treatment for...
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In a nutshell This study examined evidence for the benefits of adding chemotherapy early to hormone therapy for metastatic prostate cancer. Authors concluded that early evidence indicates a survival benefit with the addition of chemotherapy for metastatic prostate cancer. Some background Androgen deprivation therapy (ADT) is a type of hormone...
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