In a nutshell The authors aimed to determine the impact of obesity on patient outcomes following open and minimally invasive prostate surgery. The authors concluded that obesity has a large impact on complication rates in patients who received minimally invasive surgery compared to patients who received open prostate surgery. Some...
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In a nutshell The authors aimed to identify the recommended treatments for prostate cancer in men over the age of 70 years. The authors concluded that treatments for local and advanced prostate cancer in elderly men should be individualized, with focus on the health of the patient, to determine the appropriate treatment course. Some background...
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In a nutshell The authors aimed to determine guidelines for the treatment of relapsing, metastatic, and hormone-resistant prostate cancer. Some background Metastatic prostate cancer (advanced cancer) is cancer that has spread outside of the prostate to other organs of the body, despite treatment. Hormone therapy is the standard...
Read MoreIn a nutshell This phase 2 trial aims to evaluate the benefit of adding tremelimumab to durvalumab, two new types of immunotherapy, for metastatic castration-resistant prostate cancer. The main outcome to be investigated is treatment response. The trial is recruiting in several locations in Canada. The details Metastatic...
Read MoreIn a nutshell The authors aimed to determine how anxiety and uncertainty affects men with prostate cancer who are undergoing active surveillance. The authors concluded that uncertainty and urinary complications promote anxiety in men on active surveillance for prostate cancer. They also recommend patient education and management of urinary...
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In a nutshell The aim of the study was to examine if sentinel lymph node dissection (SLND) could be used to select patients with prostate cancer who would benefit from further pelvic radiation therapy and long-term androgen deprivation therapy (ADT). It was concluded that SLND could be used as a tool to determine whether patients should have more...
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In a nutshell The aim of this study was to compare the heath related quality of life (HRQOL) of patients treated with enzalutamide (Xtandi) or bicalutamide (Casodex). It was concluded that enzalutamide led to a better HRQOL in patients with metastatic castration resistant prostate cancer when compared...
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In a nutshell The aim of this study was to see if ultrasounds could be used as a tool to monitor low-risk prostate cancer patients in active surveillance. It was concluded that ultrasounds can be used to monitor changes in prostate cancer, and could extend the time between biopsies. Some background Low-risk prostate cancer is cancer that has not...
Read MoreIn a nutshell This study examined if intermittent androgen deprivation therapy (IADT) reduced the risks associated with continuous androgen deprivation therapy (CADT) in advanced prostate cancer patients. It was concluded IADT reduced the risk of heart failure and fractures. Some background Advanced prostate cancer is cancer that has spread...
Read MoreIn a nutshell The authors aimed to determine the effect of lifestyle interventions on quality of life in men with prostate cancer. The authors concluded that exercise, in particular supervised programs and resistance training, and diet interventions improved quality of life in men with prostate cancer. Some background Active treatments for...
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In a nutshell The aim of this study was to examine whether combining radiation therapy and antiandrogen therapy improved survival in patients with prostate cancer that is not cured by initial treatment. It was concluded that the combination of radiation therapy and antiandrogen therapy improved survival when compared to radiation therapy...
Read MoreIn a nutshell This phase 2 trial aims to evaluate the side effects and how well abiraterone acetate (Zytiga), niclosamide (Niclocide), and prednisone work in treating patients with hormone-resistant prostate cancer. The main outcome to be investigated is treatment response. The trial is recruiting in Sacramento (California), USA. The details...
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