In a nutshell
This study looked at the link between additional medical conditions and mortality in patients with rheumatoid arthritis (RA). The authors identified a number of specific conditions that significantly increased mortality risk in RA patients.
Some background
Patients with rheumatoid arthritis (RA) have an increased risk of mortality compared to the general population. It has been suggested that higher levels of inflammation seen in RA can increase the occurrence of other medical conditions. Some conditions seen in RA patients include depression, circulatory conditions (stroke or heart disorders), respiratory conditions (such as asthma or bronchitis), and disorders of the kidneys. Which specific condition can increase mortality risk in RA patients has not been fully studied.
Methods & findings
Data for this study was collected from 882 RA patients over 14 years. The number of additional medical conditions was recorded by patients filling in a questionnaire. Mortality rates were measured over the 14 year period.
A total of 345 patients died during the study period.
Circulatory conditions were associated with a 60% increased risk of mortality. Respiratory conditions were associated with a 43% increased risk of mortality. Mortality rates were twice as high for patients with cancer. Depression was associated with a 35% increase in the risk of mortality.
The bottom line
The authors concluded circulatory conditions, respiratory conditions, cancer, and depression all significantly increased mortality risk in RA patients. Close monitoring and suitable referral to a specialist may improve the health outcomes for patients.
The fine print
The presence of additional medical conditions was self-reported. This may be less accurate than physical examinations or examining records of the patients' medical histories.
Published By :
Arthritis Care & Research
Date :
Dec 14, 2015
