In a nutshell
This study aimed to investigate the effect of lifestyle factors (LFs) on Parkinson's disease (PD). This study found that LFs can influence PD progression and mortality.
Parkinson’s disease (PD) affects the nerve cells in the brain that produce a substance called dopamine. This results in symptoms such as muscle rigidity, tremors, and changes in speech and walk. LFs may contribute to the development of PD. The factors that lead to progression are still unknown.
Methods & findings
This study included 244 patients. They were followed up for an average of 5.3 years. Mortality and memory and reasoning functions were monitored. Telephone interviews were held to ask about smoking, drinks with caffeine, physical activity level and participation in competitive sports.
Coffee, caffeinated tea, moderate alcohol consumption, and physical activity were protective factors. They protected against mental decline or mortality. Smoking and heavy alcohol consumption were associated with increased risks. Those who never drank were also at an increased risk. Current cigarette smoking was associated with faster memory and reasoning functions decline.
The bottom line
This study found that LFs can influence PD progression and mortality.
The fine print
Mortality causes were not evaluated. They might have not been related to PD.
Published By :
Movement disorders: official journal of the Movement Disorder Society
Jan 01, 2019
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