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Posted by on Sep 13, 2018 in Parkinson's Disease | 0 comments

In a nutshell

This study investigated if low levels of vitamin D are associated with symptoms in the sense of smell of patients with Parkinson´s disease (PD). Researchers suggested that low levels of vitamin D are associated with a dysfunction in the sense of smell.  

Some background

PD is caused by the loss of certain brain cells. The symptoms can be physical, such as tremors to muscle rigidity. However, non-physical symptoms such as memory problems are also present in these patients.

Vitamin D is essential for healthy bones. Recent studies have shown that vitamin D might be involved in PD causing symptoms such as orthostatic hypotension (low blood pressure that happens when you stand up). However, it is not clear if vitamin D is associated with symptoms regarding the sense of smell in patients with PD.

Methods & findings

This objective of this study was to investigate the link between vitamin D and an abnormal sense of smell in patients with PD. 

This study included information on 39 patients with PD that have not been treated. These patients underwent smell identification tests. Vitamin D levels in the blood were measured in each patient.

The authors of the study found that lower sense of smell was strongly associated with lower levels of vitamin D. Stronger and more frequent changes in the ability to taste and smell were linked to lower levels of vitamin D.

The bottom line

This study determined that low levels of vitamin D are associated with changes in the sense of smell in patients with PD.

The fine print

This study did not determine the exact relationship between vitamin D and PD. Further studies are needed to determine if the correction of vitamin D levels can help improve symptoms in patients with PD. 

Published By :

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Date :

Aug 19, 2018

Original Title :

Serum 25-hydroxyvitamin D3 level may be associated with olfactory dysfunction in de novo Parkinson’s disease.

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