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Posted by on Sep 26, 2017 in Non-Hodgkin lymphoma | 0 comments

In a nutshell

This study looked at how anxiety and depression influence the quality of life of patients with diffuse large-B cell lymphoma. The study concluded that anxiety, depression, and unmet patient needs negatively impact the physical and emotional wellbeing of patients.

Some background

Diffuse large B-cell lymphoma (DLBCL) is a common type of non-Hodgkin lymphoma. The average age at DLBCL diagnosis is 71 years old. Patients often must undergo rigorous and tiring treatments for their cancer. Patients may have unmet needs or experience depression and anxiety. These can negatively impact other parts of their life.

It is unclear the exact role that anxiety, depression, and unmet patient needs have on quality of life (QoL). More research is needed to determine how patient QoL is impacted by anxiety, depression, and unmet patient needs. 

Methods & findings

Patients with DLBCL were twice contacted to complete a QoL survey. 983 patients with DLBCL were eligible to complete the surveys. (791 patients with multiple myeloma also completed the survey.) The first survey was given on average 7 months after initial diagnosis. The second survey was given on average 8.5 months after the first survey. 258 patients completed both surveys.

On the first survey, 15% of patients experienced anxiety. 18% of patients experienced depression. 30% said that they had unmet psychological and emotional needs. 30% said that they had unmet daily living needs. 11% said that they had an unmet patient care need.

There was an association between anxiety, depression, and unmet supportive needs mentioned on the first survey and a lower quality of life score at the time of the second survey. 

The bottom line

The authors concluded that patients have worse physical and emotional well-being in later months when they have unmet care needs, anxiety, and depression during treatment. 

What’s next?

Please discuss with your doctor ways to monitor and address feelings of anxiety and depression during your treatment.

Published By :

European Journal of Haematology

Date :

Aug 21, 2017

Original Title :

Distress and unmet needs during treatment and quality of life in early cancer survivorship: a longitudinal study of haematological cancer patients.

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