In a nutshell
This study investigated if other medical conditions (comorbidities, COMs) affect sperm production (SP).
They found that infertile men were more likely to have COMs and their treatment improved SP.
Some background
Male infertility accounts for up to 50% of fertility problems. In many cases, it is not possible to find the cause of infertility. Sperm production (SP) may be impaired in some patients. The cause of reduced SP is not clear. Recent studies suggest that other conditions may contribute to infertility and reduced SP. Other medical conditions are called comorbidities (COMs).
Men with reduced SP also have higher mortality rates. It is unclear if COMs have an effect on SP.
Methods & findings
This study included 3,328 infertile men and 452 fertile men. Semen samples were analyzed to determine SP and sperm quality (SQ). Details on COMs were obtained from patient records.
Men with infertility had higher COM rates (21.7%) than fertile men (9.1%). High blood pressure was the most common COM. Other common COMs included diabetes, dialysis (a treatment for patients with kidney failure) and inflammatory bowel disease. Azoospermia (no sperm produced) rates were higher in men with COMs (11.4% vs. 8.8%). This was higher in men with skin disease (27% vs. 13%).
Treatment for high blood pressure improved SP after 6 months. Treatment for other COMs improved SP in 44.4% of men.
The bottom line
The authors concluded that infertile men were more likely to have COMs and their treatment improved SP.
The fine print
This study looked back at medical records. This means some parameters could not be controlled. It is unclear if other factors may also affect the link between SP and COMs. Further investigation is needed.
What’s next?
If you have any concerns regarding fertility treatment, please consult with your physician.
Published By :
Fertility and Sterility
Date :
Nov 01, 2018
