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Posted by on Dec 7, 2016 in Hypertension | 0 comments

In a nutshell

This study looked at the effect of the milk proteins, whey and calcium, on blood pressure and cardiovascular risk factors (affecting the heart and blood vessels) in patients with hypertension. The authors concluded that taking milk protein supplements reduced blood pressure and risk of cardiovascular disease in pre-hypertensive and mildly hypertensive patients.

Some background

Cardiovascular disease (CVD) refers to conditions affecting the heart and blood vessels. The risk of developing CVD is higher in patients with hypertension. If left untreated, CVD can lead to strokes or, in extreme cases, heart failure or death. Managing hypertension in its early stages could reduce these risks.

Patients with pre-hypertension have consistently increased blood pressure and are considered at risk of developing hypertension. Pre-hypertension and mild hypertension is often managed by making lifestyle changes. These include weight reduction and increasing physical activity. Some dietary changes, such as increasing milk intake, are also believed to help lower blood pressure and reduce the risk of CVD. Patients can easily increase their intake of milk protein by taking supplements such as whey or calcium.

Methods & findings

38 patients with pre-hypertension or mild hypertension were included in this study. Participants were randomly assigned to receive either calcium supplements, whey supplements, or a food starch sachet (control group) over a period of 8 weeks. Changes in systolic blood pressure (pressure when the heart is contracting) and diastolic blood pressure (pressure when the heart is between beats) were measured over a 24-hour period. Changes in artery functon were measured using flow mediated dilation (FMD) to determine CVD risk. Increases in FMD indicates a decrease in CVD risk.  

Whey protein significantly reduced 24-hour systolic blood pressure by 3.9 mm Hg and reduced diastolic blood pressure by 2.5 mm Hg.

FMD increased significantly after the intake of both whey and calcium when compared to the control group. FMD increased by 1.31% in the whey protein group and 0.83% in the calcium group. However, supplements did not have a significant effect on a measure of arterial stiffness.

Both whey and calcium significantly lowered total cholesterol. Whey protein significantly reduced triacylglycerol (the main element in body fats). 

The bottom line

This study concluded that milk proteins taken as supplements can reduce a measure of CVD risk and lower blood pressure in patients with early-stage hypertension.

The fine print

Larger studies are needed to confirm these results. The doses of protein given in this study were high, above the normal intake of the general population.

Published By :

The American Journal of Clinical Nutrition

Date :

Oct 26, 2016

Original Title :

Whey protein lowers blood pressure and improves endothelial function and lipid biomarkers in adults with prehypertension and mild hypertension: results from the chronic Whey2Go randomized controlled trial.

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