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Posted by on Jan 18, 2019 in Hypertension | 0 comments

In a nutshell

This study investigated the effectiveness of a combined nutraceutical (BPLN®) for the management of hypertension. They found that this supplement reduced blood pressure in patients with hypertension. 

Some background

Hypertension or high blood pressure is a very common condition. Managing blood pressure (BP) levels prevents damage to the cardiovascular system (heart and circulation). Hypertension can be treated using medication and/or lifestyle changes (LC). LC includes changing diet or increasing physical activity.

LC’s can be difficult to maintain long-term. Relying on LC to manage BP levels may not be effective. Some studies suggest anti-hypertensive supplements (AHS) could be useful at helping BP management. AHS contain supplements or nutraceuticals that may reduce BP. BPLN® is an AHS that contains beetroot dry extract, magnesium, and vitamins C, B1, and D. It is unclear if BPLN® can improve BP management in patients with hypertension. 

Methods & findings

This study included 36 patients with pre-hypertension or first-degree hypertension. They were not taking any medication to treat hypertension. All patients were instructed on a healthy diet and exercise regimen to manage BP levels. After 4 weeks of LC, patients were randomly assigned to take either BPLN® or a placebo. This was given for 16 weeks. Systolic (pressure of blood leaving the heart) and diastolic (pressure of blood re-filling the heart) BP were measured before and after treatment. 

Patients taking BPLN® had a significant reduction in morning BP and evening systolic BP at the end of the study compared to the beginning of the study and the placebo group. Patients in the placebo group also had a reduction in BP at the end of the study. There were no reported adverse events in patients taking BPLN® or placebo. 

The bottom line

The authors concluded that BPLN® was effective in lowering blood pressure in patients with hypertension.

The fine print

This study was the first of its kind and included a small number of patients. Further studies are needed to determine the effectiveness of BPLN®

What’s next?

If you have any concerns regarding BP management, please consult with your doctor. 

Published By :

High blood pressure & cardiovascular prevention: the official journal of the Italian Society of Hypertension

Date :

Nov 23, 2018

Original Title :

Is it Possible to Significantly Modify Blood Pressure with a Combined Nutraceutical on Top of a Healthy Diet? The Results of a Pilot Clinical Trial.

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