The implantation of inflatable penile prosthesis (IPP) to treat erectile dysfunction in men with Peyronie’s disease

This study aimed to investigate the efficacy and satisfaction of implantation of an inflatable penile prosthesis (IPP) to treat erectile dysfunction (ED) in men with Peyronie's disease (PD). This study found that patients with PD and ED can safely and effectively have an IPP placed.

Peyronie's disease (PD) is penis problem caused by scar tissue, called plaque, that forms inside the penis. It can result in a bent, rather than straight, erect penis. Most men with PD can still have sex. But for some, it can be painful and can cause erectile dysfunction (ED). An inflatable penile prosthesis (IPP) is a device implanted in the penis that can be inflated to create an erection. It is still not known is IPP could be an effective treatment for ED in men with PD. 

This study included 250 men with PD and 1180 men with ED in total. They all had IPP placements. Men completed 5 validated questionnaires at the beginning of the study and annually for 5 years to evaluate patients satisfaction.

At the beginning of the study, 19.3% of men with PD reported being depressed. This decreased to 10.5% at 1 year follow-up. More than 83% of patients with PD were satisfied or very satisfied at 1 and 2 year follow-ups. In addition, more than 88% of patients with PD were using their device at the 1 and 2-year follow-up visits. 

This study found that patients with PD and ED can safely and effectively have an IPP placed.

All surgeons involved implanted these devices very frequently. These results may not be applicable to every hospital. Some of the data collection was not mandatory, such as the depression reporting.