Extracorporeal shock wave therapy: can it treat symptoms in men with Peyronie’s disease?

This study investigated the effectiveness of extracorporeal shock wave therapy (ESWT) in men with Peyronie’s disease (PD).

They found that ESWT is safe and effective in these patients. 

Peyronie’s disease (PD) is a condition that causes a curvature in the penis. The curve or bend is caused by a build-up of fibrous tissue on the penis shaft. These are called plaques. PD can lead to pain and erectile dysfunction (ED). It is unclear what causes PD. There are few treatment options for men with PD. There is only one approved drug called collagenase clostridium hystoliticum (CCH). It is an enzyme that breaks up collagen protein. Collagen is one of the components of plaques in PD.

Some studies suggest alternative approaches might be useful. Extracorporeal shock wave therapy (ESWT) is a minimally invasive technique. It involves using acoustic waves to deliver high energy to the affected area. Studies have shown that this stimulates healing and tissue repair. It is unclear if ESWT is safe and effective in the treatment of PD.

This study included 325 men with PD. All patients underwent ESWT. Patients were evaluated at the beginning of the study and 3 months after treatment. Penile curvature and sexual function were measured. Patients were also asked about the psychological and physical impact of PD.

ESWT led to a significant reduction in plaque size at 3 months. There was also a decrease in penis curvature. Sexual function scores improved in all patients. There was also an improvement in psychological and physical scores. No treatment-related side effects were reported. 

The authors concluded that ESWT is safe and effective in patients with Peyronie's disease.

This study did not have a comparative group. It is unclear if ESWT is more or less effective in certain types of PD. More investigation is needed. 

If you have any concerns regarding PD, please consult with your doctor.