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Posted by on Dec 7, 2019 in Colorectal cancer | 0 comments

In a nutshell

This study investigated the factors predictive of a permanent stoma (PS; an opening in the body that allows waste to exit) in patients with rectal cancer. Researchers suggested that tumor distance from the anus was associated with PS in these patients.

Some background

Colorectal cancer is the third most common cancer worldwide. The standard treatment is chemotherapy and surgery. A stoma may be created in patients with rectal dysfunction. A stoma is a small opening on the surface of the abdomen in order to divert the flow of feces. These are then collected in a bag attached to the stoma. It may have a significant impact on the quality of life. It is important to investigate the factors that may predict a permanent stoma (PS) in patients undergoing colorectal cancer surgery.

Methods & findings

This study included 577 patients with rectal cancer. The average follow-up time was 57.4 months. A PS was created in 144 (25%) of the patients. 

Patients with PS had a shorter tumor distance from the anus and larger tumor size. Patients with shorter tumor distance from the anus had a 47% increase in the odds of having a PS. The function of the anus before the surgery did not affect outcomes after surgery.

The bottom line

This study concluded that tumor distance from the anus predicts the creation of PS in patients with rectal cancer.

The fine print

This study was based on medical records. Some information might have been incomplete. This might affect the results.

Published By :

Colorectal Disease

Date :

Nov 07, 2019

Original Title :

Predictors of permanent stoma creation in patients with mid or low rectal cancer: results of a multicentre cohort study with preoperative evaluation of anal function.

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