Metabolic syndrome and smoking are associated with nocturia after transurethral resection of the prostate

This study aimed to evaluate the link between smoking, metabolic syndrome (MetS) and side-effects after prostate surgery. This study found smoking and MetS led to a higher risk of nocturia (waking at night to urinate).

Transurethral resection of the prostate (TURP) is a surgery used to treat urinary problems due to an enlarged prostate. It removes the prostate parts blocking the urine flow through the penis. Nocturia is an urge to urinate at night. Patients who have an enlarged prostate can have nocturia. MetS is a group of characteristics including high blood pressure, cholesterol and being overweight. 

It is unknown if MetS and smoking could lead to persistent nocturia after TURP. 

This study included 102 patients. All patients had an enlarged prostate and experienced urinary symptoms, including nocturia. All patients underwent TURP. 39% of patients had MetS. 61% of patients were smokers.

After TURP, 42% of patients reported moderate to severe nocturia. 58% of patients who had MetS had this side-effect. 58% of patients who smoked also complained of this symptom. 

This study found that MetS and smoking increased the risk of nocturia after TURP.

Nocturia in this study was evaluated through questionnaires. Information collected in this way is not always reliable. Further studies are needed.