In a nutshell This study investigated the prescribed doses of tyrosine kinase inhibitors (TKIs) and the outcomes of elderly patients with chronic myeloid leukemia (CML). The study concluded that the currently prescribed TKI dose might be higher than necessary in elderly patients. Some background TKIs such as imatinib (Glivec), dasatinib...
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In a nutshell This article investigated the relationship between electronic cigarette (EC) use and myocardial infarction (MI; heart attack). The authors concluded that EC use is associated with an increased risk of having had an MI. Some background People who smoke normal cigarettes are 2 to 5 times more likely to have an MI. It is...
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In a nutshell This article investigated the safety and effectiveness of electroacupuncture (EA) compared with pelvic floor muscle training (PFMT) and solifenacin (Vesicare) in women with mixed urinary incontinence (MUI). The authors concluded that EA is safer and may be more efficacious with the effect lasting up to 36 weeks. Some background...
Read MoreIn a nutshell This article investigated the link between symptom severity (SS) and the success of conservative management (CM) in women with urinary incontinence (UI). The authors concluded that mild SS was associated with improved CM success. Some background Overactive active bladder (OAB) is a condition where there is a frequent feeling...
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In a nutshell This article investigated the factors that can predict treatment success of percutaneous tibial nerve stimulation (PTNS) for overactive bladder (OAB). The authors concluded that a history of depression/anxiety and severe urgency urinary incontinence (UUI; needing to urinate urgently) before treatment predicted a higher chance of...
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In a nutshell This article investigated the convenience of an at-home exercise and bladder training program in elderly women with urinary incontinence (UI). The authors concluded that this may be a convenient and favorable treatment for elderly women with UI. Some background UI is the involuntary leakage of urine. Control over...
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In a nutshell This article investigated the safety and effectiveness of nivolumab (Opdivo) in combination with stereotactic body radiotherapy (SBRT) for patients with locally advanced melanoma unsuitable for surgery. The authors concluded that this therapy is effective with manageable side effects in these...
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In a nutshell This article compared the safety and effectiveness of insulin glargine (Lantus) at two different doses in the management of type 1 diabetes (T1D). The authors concluded that the effectiveness and safety of both doses were similar. Some background In T1D the body does not make insulin and cannot lower the blood...
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In a nutshell This article investigated the safety and effectiveness of sitagliptin (Januvia) in the management of type 2 diabetes (T2D) in elderly patients on insulin. The authors concluded that the addition of sitagliptin is effective and safe in all patients receiving it as add-on therapy to insulin. Some background In type 2...
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In a nutshell This study examined if anti-androgen therapy for prostate cancer is associated with depression. This study concluded that the risk of depression is increased in these patients. Some background Anti-androgen therapy or androgen deprivation therapy (ADT) is commonly used in the treatment of prostate cancer. Androgens (such as...
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In a nutshell This study examined if single fraction, high dose brachytherapy for low and medium risk prostate cancer is safe and effective. This study concluded that this treatment for prostate cancer is safe and effective, however, it should not be used outside of clinical trials. Some background Prostate cancer can be treated using...
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In a nutshell This study examined if Vesomni (also known as Urizia/Volutsa) can improve quality of life in men with lower urinary tract symptoms. This study concluded Vesomni can improve quality of life in these men. Some background Lower urinary tract symptoms (LUTS) can have a negative impact on daily life. These symptoms can...
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