In a nutshell This review compared the outcomes of 2 techniques for robotic-assisted radical prostatectomy (RARP; complete removal of the prostate gland using robotic arms): Retzius-sparing (RS)-RARP and conventional (C)-RARP in patients with localized prostate cancer (PCa). The analysis showed that RS-RARP was associated with improved urinary...
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Searching for patients with confined prostate cancer to trial a cryoablation procedure
In a nutshell This trial is looking to examine the use of a new treatment software (UroNAV Ablation) system in treating confined prostate cancer with cryoablation. The main outcomes to be measured will be device/treatment-related complications and tumor control. This trial is being carried out in New York, US. The details Localized...
Read MoreComparing the effectiveness of apalutamide, darolutamide and enzalutamide in treating nonmetastatic castration-resistant prostate cancer
In a nutshell The study compared outcomes of apalutamide (A; Erleada), darolutamide (D; Nubeqa), and enzalutamide (E; Xtandi) in treating nonmetastatic castration-resistant prostate cancer (nmCRPC). The authors found that A and E had better metastasis-free survival (MFS) compared to D. Some background Men with CRPC fail to respond to...
Read MoreComparing cryosurgery and hormonal therapy for locally recurrent prostate cancer after radiotherapy
In a nutshell This study compared local cryosurgery (CRYO) against androgen deprivation therapy (ADT) for the treatment of locally recurring prostate cancer (LRPC). The study found local cryosurgery had a longer overall survival (OS) when compared to ADT. Some background LRPC is cancer that has re-occurred in the prostate gland...
Read MoreLooking for patients with prostate cancer to test a type of radiation treatment
In a nutshell This phase 3 trial will compare the safety and effectiveness of hypofractionated radiotherapy (HF-RT) to standard radiotherapy (RT). The main outcomes will be the number of grade 2 side effects and disease control. This trial is recruiting in Houston, Texas, United States. The details Radiation therapy (RT) is a...
Read MoreSurvival after radiotherapy vs. prostate surgery for intermediate-risk prostate cancer.
In a nutshell This study aimed to investigate the outcomes of intermediate risk-risk prostate cancer after different treatments. This study concluded that prostate surgery might have a higher survival than radiotherapy. Some background There a several options to treat intermediate-risk prostate cancer (IR-PC). Radical prostatectomy (RP; surgery to...
Read MoreLooking at different types of radiation therapy for intermediate risk prostate cancer
In a nutshell This trial evaluates the effectiveness of radiation therapy delivered from outside the body for the treatment of prostate cancer. The main outcomes of this trial are the number of patients who have no damage to genital or urinary organs and survival without cancer. This trial is taking place in various sites across the USA and...
Read MoreLooking for patients with advanced prostate cancer to test a type of radiation therapy
In a nutshell This trial evaluates a specific type of radiation therapy for advanced prostate cancer. The main outcome to be measured is whether or not the therapy will damage the surrounding organs. This trial is taking place in Pennsylvania, USA. The details Prostate cancer is an uncontrolled growth of the cells which make up the...
Read MoreLong term results discussing radiotherapy and hormone therapy treatments for patients with prostate cancer
In a nutshell This study aimed to evaluate whole pelvic radiotherapy (WPRT) compared to prostate only radiotherapy (PORT) with hormonal therapy (HT) before or after radiation for patients with intermediate- or high-risk prostate cancer. This study found that HT before radiotherapy and WPRT had superior long-term survival without cancer growing or...
Read MoreComparing robot-assisted laparoscopic prostate surgery versus open prostate surgery
In a nutshell This study aimed to compare traditional open surgery and robotic surgery to treat prostate cancer in terms of side effects. It found that there was no difference in side-effects like sexual function or urinary problems between the two surgeries. Some background Prostate surgery is a treatment option for prostate cancer. This surgery...
Read MoreLooking for patients with prostate cancer who have had a rise in PSA after prostate removal surgery
In a nutshell This trial is examining the effectiveness of different hormone therapy regimes for patients whose prostate specific antigen (PSA; a protein elevated in prostate cancer) levels rise after prostate removing surgery. The main outcome to be measured will be the change in PSA levels. The details The best standard treatment...
Read MoreDo side-effects vary between risk groups after treatment for localized prostate cancer?
In a nutshell This study aimed to determine whether differences in side effects reported over time in patients who had surgery or radiotherapy varied by risk group. This study found that for men with low-risk prostate cancer, radiotherapy was associated with higher sexual function scores at 3 years than surgery;...
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