In a nutshell The study investigated the effectiveness and safety of abatacept (Orencia) for patients with rheumatoid arthritis (RA). The analysis concluded that abatacept gave better results to patients with RA compared to other biologic drugs. Some background RA is a common autoimmune disorder that affects the joints. This condition...
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In a nutshell This study investigated the occurrence and baseline risk factors of cancer occurrence in patients with rheumatoid arthritis (RA) treated with tofacitinib (Xeljanz) or tumor necrosis factor inhibitors (TNFis). The data showed a higher risk of cancer development with tofacitinib treatment compared to TNFis in these patients. Some...
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In a nutshell This study investigated the effect of a Mediterranean diet (MD) intervention with physical activity on rheumatoid arthritis (RA) disease status and the risk of cardiovascular diseases in women. The data showed that a personalized MD plan along with physical activity (PA) may provide benefits to females with RA. Some background RA is a...
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In a nutshell The study evaluated the effectiveness of reducing cardiovascular events (CVE) with immunomodulatory (IM) in patients with rheumatoid arthritis (RA). The main finding was that IM showed improvements in vascular inflammation in this group of patients. Some background IMs are drugs that modify the immune system to help the body respond...
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In a nutshell This study evaluated the cost-effectiveness of low-dose prednisolone (Omnipred) at 5 mg daily in the treatment of patients with rheumatoid arthritis (RA) aged 65 years or more. The study found that a low dose of prednisolone was an effective add-on treatment for patients with RA based on similar or lower costs compared to a placebo for...
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In a nutshell This study investigated the occurrence of osteoporosis (OP) in patients with rheumatoid arthritis (RA). The authors concluded that although significant advancements were made in OP prevention, treatment and diagnosis, a high occurrence was still observed in patients with RA. Some background OP commonly occurs in patients with RA. It...
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In a nutshell This study explored the effectiveness and safety of tripterygium glycosides (TG) as a disease-modifying anti-rheumatic drug (DMARD) when combined with conventional DMARDs for treating rheumatoid arthritis (RA). The authors concluded that good safety and better improvements in RA symptoms were observed when TG was combined with a...
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In a nutshell This study investigated the safety and effectiveness of ABX464 (Obefazimod) in patients with active rheumatoid arthritis (RA) with inadequate responses to methotrexate (Trexall) or anti-tumor necrosis factor alpha (anti-TNFα) treatment. The authors concluded that ABX464 was safe and well-tolerated with promising effectiveness in these...
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In a nutshell This study compared the occurrence of infections and identified their risk factors in patients with rheumatoid arthritis (RA) that were treated with tofacitinib (Xeljanz) against those given a tumor necrosis factor inhibitor (TNFi). The data showed that serious and non-serious infections were higher in patients that received...
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In a nutshell This study evaluated the 7-year follow-up remission rate and maintenance in patients with rheumatoid arthritis (RA) under real-life conditions and identified factors related to long-term remission. The authors concluded that at 7 years nearly twice as many patients were in remission than at 1 year of follow-up and those patients had mainly...
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In a nutshell This study evaluated the effectiveness and safety of rituximab (Rituxan) biosimilar HLX01 combined with methotrexate (MTX; Trexall) in patients with moderate to severe rheumatoid arthritis (RA) following inadequate responses to MTX. The study showed that HLX01 added to MTX resulted in improvements compared to placebo in these...
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In a nutshell This study assessed the effectiveness and safety of daily administered prednisolone (Prelone) at a dose of 5 mg, as an add-on to the standard of care (SOC) in older patients with rheumatoid arthritis (RA). The authors concluded that low-dose prednisolone added to SOC had long-term benefits in these patients with a favorable balance of...
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